Publications
Selected works from the Bernkop Lab
Last updated: August, 2025. For the latest version, please check our Google Scholar profile.
Oral Delivery Of Peptide And Protein Drugs – Oral Delivery Of GLP-1 Analogue
Bernkop-Schnürch, A.
Formulation & Delivery Europe 2025 part of Discovery & Development Europe, 2025
Speaker – European Peptide Drug Summit 2025
Bernkop-Schnürch, A.
European Peptide Drug Summit, 2025
Thiolated Cyclodextrins in Drug Delivery
Bernkop-Schnürch, A.
EuroCD 2025 – 8th European Cyclodextrin Conference, Milano, Italy, 2025
Quaternary ammonium-modified dextran: a unique biodegradable mucoadhesive polymer
Afzal, K. B.; Kali, G.; Haris, M.; Schmidt, M. R.; Ebert, M.; Stefan, E.; Bernkop-Schnürch, A.
European Journal of Pharmaceutics and Biopharmaceutics, 2025
Highly thiolated corn starch for enhanced mucoadhesion and permeation
Davoudi, Z.; Kali, G.; Braun, D.; Azizi, M. H.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 2025
Self-emulsifying drug delivery systems: A comparison of dry and wet reverse micelles
Eczacioglu, N.; Postina, A.; Ebert, M. L.; Laffleur, F.; Kali, G.; Seybold, A.; Bernkop-Schnürch, A.
Acta Biomaterialia, 2025
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Haddadzadegan, S.; Summonte, S.; Ricci, F.; Sandmeier, M.; Bernkop-Schnürch, A.
Advanced Functional Materials, 2025
Optimizing hydrophilic drug incorporation into SEDDS using dry reverse micelles: a comparative study of preparation methods
Lindner, S.; Ricci, F.; Sandmeier, M.; Holm, R.; Michalowski, C. B.; Washburn, N.; Sun, D.; Di Pretoro, G.; Bernkop-Schnürch, A.
Drug Delivery and Translational Research, 2025
Design and in vitro evaluation of thiolated alginates with N-acetyl-L-cysteine/L-cysteine substructures
Mackaya-Navarro, L.; Knoll, P.; Campos-Requena, V. H.; Hidalgo, P. I.; Bernkop-Schnürch, A.
Journal of Pharmaceutical Sciences, 2025
Oral peptide drug delivery: design of SEDDS providing a protective effect against intestinal membrane-bound enzymes
Postina, A.; To, D.; Zöller, K.; Bernkop-Schnürch, A.
Drug Delivery and Translational Research, 2025
Mixed dry reverse micelles: potential carriers for oral protein delivery via SEDDS
Ricci, F.; Lindner, S.; Summonte, S.; Holm, R.; Sun, D.; Washburn, N.; Michalowski, C. B.; Di Pretoro, G.; Bernkop-Schnürch, A.
Drug Delivery and Translational Research, 2025
Exploring the potential of vaginal drug delivery: innovations, efficacy, and therapeutic prospects
Sanchez Armengol, E.; Veider, F.; Millotti, G.; Kali, G.; Bernkop-Schnürch, A.; Laffleur, F.
Journal of Pharmacy and Pharmacology, 2025
Assessing the potential of chlorido[N,N''-bis(salicylidene)-1,2-phenylenediamine]iron(III): Exploring delivery through lipid-based nanocarriers
Schmidt, M. R.; Bernkop-Schnürch, A. D.; Stengel, D.; Kiechle, M. A.; Afzal, K. B.; Seybold, A.; Hermann, M.; Kircher, B.; Bernkop-Schnürch, A.
European Journal of Pharmaceutical Sciences, 2025
Self-Emulsifying delivery systems for oral administration of exenatide: Hydrophobic ion pairs vs. Dry reverse micelles
Schmidt, M. R.; Ebert, M. L.; Kiechle, M. A.; Zöller, K.; Laffleur, F.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 2025
Design of lipid-based formulations for oral delivery of a BASP1 peptide targeting MYC-dependent gastrointestinal cancer cells
To, D.; Steinbring, C.; Weber, L. I.; Ricci, F.; Polidori, I.; Postina, A.; Hartl, M.; Bernkop-Schnürch, A.
Journal of Controlled Release, 2025
Addressing the polycation dilemma in drug delivery: charge-converting liposomes
Truszkowska, M.; Saleh, A.; Ebert, M. L.; Kali, G.; Bernkop-Schnürch, A.
Journal of Materials Chemistry B, 2025
Peptide drug delivery: Permeation behaviour and intracellular fate of hydrophobic ion pairs in self-emulsifying drug delivery systems
Truszkowska, M.; Ebert, M. L.; Afzal, K. B.; Györgyi, V.; Bernkop-Schnürch, A.
European Journal of Pharmaceutical Sciences, 2025
Exploring glutathione-decorated micelles for drug delivery: A promise for enhanced cellular uptake
Truszkowska, M.; Reisenberger, E.; Kali, G.; Stengel, D.; Saleh, A.; Seybold, A.; Kipura, T.; Kwiatkowski, M.; Bernkop-Schnürch, A.
Colloids and Surfaces B: Biointerfaces, 2025
Biomedical applications of functional hydrogels: Innovative developments, relevant clinical trials and advanced products
Zöller, K.; To, D.; Bernkop-Schnürch, A.
Biomaterials, 2025
Enhanced cytotoxicity of exo- and endogenous compounds by hitchhiking lipid-based nanocarriers
Zöller, K.; Lindner, S.; To, D.; Postina, A.; Bernkop-Schnürch, A.
Journal of Drug Delivery Science and Technology, 2025
Plenary Speaker
Bernkop-Schnürch, A.
2nd International Conference on Nanotechnology & Materials (NanoMatConfEx), 2024
Development and characterization of self-emulsifying drug delivery system of Physalis peruviana calyces extract with high mucus permeating properties
Rodríguez, I. A.; Cardona, M. I.; Domínguez, G. P.; Echeverry, S. M.; Valderrama, I. H.; Bernkop-Schnürch, A.; Aragón, D. M.
Handbook of Goldenberry (Physalis Peruviana), 2024
RESINIFERATOXIN COMPOSITIONS
Bernkop-Schnürch, A.; Valdenaire, O.; Giller, T.
US Patent App. 20240382449, 2024
Self-emulsifying drug delivery systems containing sulfate-based surfactants: Are they responsive to alkaline phosphatase?
Ahmad Saleh, Zeynep Burcu Akkuş-Dağdeviren, Florina Veider, Nuri Ari Efiana, Andreas Bernkop-Schnürch
Journal of Drug Delivery Science and Technology 96, 105717, 2024
Design of Mucoadhesive polymers: Design of S-protected thiolated cyclodextrin-based hydrogels
Andrea Fürst, Gergely Kali, Aida Dizdarević, Daniel Stengel, Andreas Bernkop-Schnürch
International Journal of Pharmaceutics 656, 124075, 2024
Therapeutic effect of 5-ASA and hesperidin-loaded chitosan/Eudragit® S100 nanoparticles as a pH-sensitive carrier for local targeted drug delivery in a rat model of ulcerative colitis
Armana Abdollahy, Majid Salehi, Solmaz Mahami, Andreas Bernkop-Schnürch, Hamid Vahedi, Anneh Mohammad Gharravi, Mohsen Mehrabi
International Journal of Pharmaceutics 652, 123838, 2024
Simulated Gastrointestinal Fluids Impact the Stability of Polymer-Functionalized Selenium Nanoparticles: Physicochemical Aspects
Atiđa Selmani, Nives Matijaković Mlinarić, Salvatore Fabio Falsone, Ivan Vidaković, Gerd Leitinger, Ida Delač, Borna Radatović, Ivan Nemet, Sanda Rončević, Andreas Bernkop-Schnürch, Tomislav Vuletić, Karin Kornmueller, Eva Roblegg, Ruth Prassl
International Journal of Nanomedicine, 2024
Effects of polymeric surfactants with low HLB values on drug and excipient release from self-emulsifying drug delivery systems
Bao Le-Vinh, Nguyet-Minh Nguyen Le, Thi Nhu Quynh Phan, Barbara Matuszczak, Andreas Bernkop-Schnürch
Journal of Drug Delivery Science and Technology 91, 105199, 2024
Effects of excipients on the interactions of self-emulsifying drug delivery systems with human blood plasma and plasma membranes
Bao Le-Vinh, Nguyet-Minh Nguyen Le, Thi Nhu Quynh Phan, Hung Thanh Lam, Andreas Bernkop-Schnürch
Drug Delivery and Translational Research 14 (11), 3200-3211, 2024
The power of sulfhydryl groups: Thiolated lipid-based nanoparticles enhance cellular uptake of nucleic acids
Daniel Stengel, Arne M Jörgensen, Ilaria Polidori, Paul Kapitza, Fabrizio Ricci, Andreas Bernkop-Schnürch
Journal of Colloid and Interface Science 654, 1136-1145, 2024
Limited cellular uptake of liposomes: Might thiolated phospholipids hold the key?
Daniel Stengel, Zeliha Duygu Özdal, Martyna Truszkowska, Ahmad Saleh, Anna Seybold, Andreas Bernkop-Schnürch
International Journal of Pharmaceutics 667, 124812, 2024
Antibiotic-Polyphosphate Nanocomplexes: A Promising System for Effective Biofilm Eradication
Dennis To, Mariana Blanco Massani, Débora C Coraça-Huber, Anna Seybold, Fabrizio Ricci, Katrin Zöller, Andreas Bernkop-Schnürch
International Journal of Nanomedicine, 2024
Charge-converting nanocarriers: Phosphorylated polysaccharide coatings for overcoming intestinal barriers
Florina Veider, Dennis To, Ahmad Saleh, Flavia Laffleur, Gergely Kali, Dominik Hense, Oliver I Strube, Andreas Bernkop-Schnürch
International Journal of Biological Macromolecules 281, 136308, 2024
Charge‐reversible nanoparticles: advanced delivery systems for therapy and diagnosis
Florina Veider, Eva Sanchez Armengol, Andreas Bernkop‐Schnürch
Small 20 (3), 2304713, 2024
Overcoming intestinal barriers by heparanase-responsive charge-converting nanocarriers
Florina Veider, Katrin Zöller, Ahmad Saleh, Andreas Bernkop-Schnürch
International Journal of Pharmaceutics 651, 123817, 2024
Inhibition of P-glycoprotein-mediated efflux by thiolated cyclodextrins
Florina Veider, Soheil Haddadzadegan, Eva Sanchez Armengol, Flavia Laffleur, Gergely Kali, Andreas Bernkop-Schnürch
Carbohydrate Polymers 327, 121648, 2024
S-protected thiolated surfactants enhancing surface properties of lipid-based nanocarriers
Gennaro Balenzano, Giuseppe Francesco Racaniello, Miriam Domenica Panzarino, Patrick Knoll, Martyna Truszkowska, Valentino Laquintana, Andreas Bernkop-Schnürch, Nunzio Denora
Journal of Drug Delivery Science and Technology 95, 105540, 2024
Disulfide stoppered polyrotaxanes with enhanced cellular uptake and intracellular cyclodextrin release
Gergely Kali, Alexander H Mayer, Dennis To, Martyna Truszkowska, Raphael Plangger, Markus Gallei, Andreas Bernkop-Schnürch
Carbohydrate Polymer Technologies and Applications 8, 100586, 2024
Enhanced Mucoadhesion of Thiolated β-Cyclodextrin by S-Protection with 2-Mercaptoethanesulfonic Acid
Gergely Kali, Ali Magdi Mahmoud Mahmoud Taha, Emiliano Campanella, Martyna Truszkowska, Soheil Haddadzadegan, Nunzio Denora, Andreas Bernkop-Schnürch
ACS Omega 9 (5), 5819-5828, 2024
Mucoadhesive poly (ethylene glycol)-based biodegradable polyesters with in-chain model drug
Gergely Kali, David Gintsburg, Lana Molnar, Annabelle Knoll, Andreas Bernkop-Schnürch
Journal of Drug Delivery Science and Technology 102, 106332, 2024
Cyclodextrins and derivatives in drug delivery: New developments, relevant clinical trials, and advanced products
Gergely Kali, Soheil Haddadzadegan, Andreas Bernkop-Schnürch
Carbohydrate Polymers 324, 121500, 2024
Histidine-based ionizable cationic surfactants: novel biodegradable agents for hydrophilic macromolecular drug delivery
Ilaria Polidori, Dennis To, Gergely Kali, Andreas Bernkop-Schnürch
Drug Delivery and Translational Research 14 (9), 2370-2385, 2024
Development and characterization of self-emulsifying drug delivery system of Physalis peruviana calyces extract with high mucus permeating properties
Ingrid Andrea Rodríguez, María I Cardona, Gina P Domínguez, Sandra M Echeverry, Ivonne H Valderrama, Andreas Bernkop-Schnürch, Diana M Aragón
Handbook of Goldenberry (Physalis Peruviana), 433-446, 2024
Fluorescent hydrophobic ion pairs: A powerful tool to investigate cellular uptake of hydrophobic drug complexes via lipid-based nanocarriers
Katrin Zöller, Anna Karlegger, Martyna Truszkowska, Daniel Stengel, Andreas Bernkop-Schnürch
Journal of Colloid and Interface Science 654, 174-188, 2024
Biomedical applications of functional hydrogels: Innovative developments, relevant clinical trials and advanced products
Katrin Zöller, Dennis To, Andreas Bernkop-Schnürch
Biomaterials, 122718, 2024
Design of charge converting lipid nanoparticles via a microfluidic coating technique
Katrin Zöller, Soheil Haddadzadegan, Sera Lindner, Florina Veider, Andreas Bernkop-Schnürch
Drug Delivery and Translational Research 14 (11), 3173-3185, 2024
Preparation, Characterization, and Anticancer Activity Assessment of Chitosan/TPP Nanoparticles Loaded with Echis carinatus Venom
Maral M Kancha, Mohsen Mehrabi, Fatemeh Sadat Bitaraf, Hamid Vahedi, Morteza Alizadeh, Andreas Bernkop-Schnürch
Anti-Cancer Agents in Medicinal Chemistry 24 (7), 533-543, 2024
Preparation and characterization of PVA/chitosan nanofibers loaded with Dragon's blood or poly helixan as wound dressings
Maral Mahboubi Kancha, Mohsen Mehrabi, Faeze Aghaie, Fatemeh Sadat Bitaraf, Farzaneh Dehghani, Andreas Bernkop-Schnürch
International Journal of Biological Macromolecules 272, 132844, 2024
Enzyme-responsive nanoparticles: enhancing the ability of endolysins to eradicate Staphylococcus aureus biofilm
Mariana Blanco Massani, Dennis To, Susanne Meile, Mathias Schmelcher, David Gintsburg, Débora C Coraça-Huber, Anna Seybold, Martin Loessner, Andreas Bernkop-Schnürch
Journal of Materials Chemistry B 12 (37), 9199-9205, 2024
Synergistic antimicrobial effect of daptomycin and ethyl lauroyl arginate containing self-emulsifying drug delivery system against bacterial infections
Martyna Truszkowska, Daniel Stengel, Marlene Ramona Schmidt, Florentine Marx, Débora Coraca-Huber, Andreas Bernkop-Schnürch
Journal of Drug Delivery Science and Technology 102, 106324, 2024
Design of self-emulsifying oral delivery systems for semaglutide: reverse micelles versus hydrophobic ion pairs
Matthias Sandmeier, Fabrizio Ricci, Dennis To, Sera Lindner, Daniel Stengel, Michaela Schifferle, Saadet Koz, Andreas Bernkop-Schnürch
Drug Delivery and Translational Research, 2024
Phosphatase-degradable nanoparticles providing sustained drug release
Simona Summonte, Eva Sanchez Armengol, Fabrizio Ricci, Matthias Sandmeier, Nathalie Hock, Ayse Güclü-Tuncyüz, Andreas Bernkop-Schnürch
International Journal of Pharmaceutics 654, 123983, 2024
Thiolated Poly‐and Oligosaccharide‐Based Hydrogels for Tissue Engineering and Wound Healing
Sobia Noreen, Andreas Bernkop‐Schnürch
Advanced Functional Materials 34 (4), 2310129, 2024
Comparative Analysis of PEG‐Free and PEG‐Based Self‐Emulsifying Drug Delivery Systems for Enhanced Oral Bioavailability of Therapeutic (Poly) Peptides
Soheil Haddadzadegan, Dennis To, Arne Matteo Jörgensen, Richard Wibel, Flavia Laffleur, Andreas Bernkop‐Schnürch
Small 20 (27), 2307618, 2024
Porous starch-inulin loaded quercetin microcapsules: characterization, antioxidant activity, in-vitro release, and storage stability
Zahra Davoudi, Mohammad Hossein Azizi, Mohsen Barzegar, Andreas Bernkop-Schnürch
Journal of Pharmaceutical Sciences 113 (5), 1228-1238, 2024
Thiolated Cyclodextrins: Mimicking the Workhorses of Our Body
Bernkop-Schnürch, A.
EuroCD 2023 – 7th European Cyclodextrin Conference, Budapest, Hungary, 2023
Thiolated Polymers – Thiomers: Utilizing the most prominent bridging structure Designed by nature
Bernkop-Schnürch, A.
POLYCONF14 – 14th Hellenic Polymer Society International Conference, Thessaloniki, Greece, 2023
Biomedical Applications of Thiomers: New Developments, Relevant Clinical Trials and Advanced Products
Bernkop-Schnürch, A.
4th Polymer Conference (PolymerConf) – online programme, 2023
Polyphosphate coated nanoparticles: Enzyme-activated charge-reversal gene delivery systems
Akkuş-Dağdeviren Z.B., Arısoy S, Friedl JD, Fürst A, Saleh A, Bernkop-Schnürch A.
Int. J. Pharm., 646, 123474, 2023
Nanoarchitectonics of Layer-by-Layer (LbL) coated nanostructured lipid carriers (NLCs) for Enzyme-Triggered charge reversal
Akkuş-Dağdeviren, Z.B.; Fürst, A.; Friedl, D.J.; Tribus, M.; Bernkop-Schnürch, A.
J. Colloid & Interface Sci., 629(Pt A), 541-553, 2023
Phosphatase-degradable nanoparticles: A game-changing approach for the delivery of antifungal proteins
Akkuş-Dağdeviren, Z.B.; Saleh, A.; Schöpf, C.; Truszkowska, M.; Bratschun-Khan, D.; Fürst ,A.; Seybold, A.; Offterdinger, M.; Marx, F.; Bernkop-Schnürch, A.
J. Colloid & Interface Sci., 646, 290-300, 2023
Counterion optimization for hydrophobic ion pairing (HIP): Unraveling the key factors
Claus, V.; Sandmeier, M.; Hock, N.; Spleis, H.; Lindner, S.; Kalb, M.; Bernkop-Schnürch, A.
Int. J. Pharm., 647, 123507, 2023
Self-emulsifying drug delivery systems (SEDDS): In vivo-proof of concept for oral delivery of insulin glargine
Claus, V.; Spleis, H.; Federer, C.; Zöller, K.; Wibel, R.; Laffleur, F.; Dumont, C.; Caisse, P.; Bernkop-Schnürch, A.
Int. J. Pharm., 639, 122964, 2023
Betaine-modified hydroxyethyl cellulose (HEC): A biodegradable mucoadhesive polysaccharide exhibiting quaternary ammonium substructures
Efiana, N.A.; Kali, G.; Fürst, A.; Dizdarević, A.; Bernkop-Schnürch, A.
Eur. J. Pharm. Sci., 180, 106313, 2023
Thiolated cyclodextrins: A comparative study of their mucoadhesive properties
Fürst, A.; Kali, G.; Efiana, N.A.; Akkuş-Dağdeviren, Z.B.; Haddadzadegan, S.; Bernkop-Schnürch, A.
Int. J. Pharm., 635, 122719, 2023
Zeta potential shifting nanoemulsions comprising single and gemini tyrosine-based surfactants
Fürst, A.; Shahzadi, I.; Akkuş-Dağdeviren, Z.B.; Schöpf, A.M.; Gust, R.; Bernkop-Schnürch, A.
Eur. J. Pharm. Sci., 189, 106538, 2023
Three generations of thiolated cyclodextrins: A direct comparison of their mucus permeating and mucoadhesive properties
Haddadzadegan, S.; Knoll, P.; Wibel, R.; Kali, G.; Bernkop-Schnürch, A.
Acta Biomater., 167, 309-320, 2023
Design of biodegradable nanoparticles for enzyme-controlled long-acting drug release
Hock, N.; To, D.; Sanchez Armengol, E.; Summonte, S.; Seybold, A.; Federer, C.; Bernkop-Schnürch, A.
Journal of Drug Delivery Science and Technology, 2023
Biodegradable arginine based steroid-surfactants: Cationic green agents for hydrophobic ion-pairing
Jörgensen, A.M.; Knoll, P.; Haddadzadegan, S.; Fabian, H.; Hupfauf, A.; Gust, R.; Georg Jörgensen, R.; Bernkop-Schnürch, A.
Int. J. Pharm., 630, 122438, 2023
Self-Emulsifying Drug Delivery Systems (SEDDS) Containing Reverse Micelles: Advanced Oral Formulations for Therapeutic Peptides
Jörgensen, A.M.; Steinbring, C.; Stengel, D.; To, D.; Schmid, P.; Bernkop-Schnürch, A.
Adv Healthc. Mater (31):e2302034, 2023
Biodegradable Cationic and Ionizable Cationic Lipids: A Roadmap for Safer Pharmaceutical Excipients
Jörgensen, A.M.; Wibel, R.; Bernkop-Schnürch, A.
Small, 19(17), e2206968, 2023
Self-emulsifying drug delivery systems (SEDDS): How organic solvent release governs the fate of their cargo
Jörgensen, A.M.; Wibel, R.; Veider, F.; Hoyer, B.; Chamieh, J.; Cottet, H.; Bernkop-Schnürch, A.
Int. J. Pharm., 647, 123534, 2023
Intraoral Drug Delivery: Highly Thiolated κ-Carrageenan as Mucoadhesive Excipient
Kali, G.; Fürst, A.; Efiana, N.A.; Dizdarević, A.; Bernkop-Schnürch, A.
Pharmaceutics, 15 (7), 1993, 2023
Per-thiolated cyclodextrins: Nanosized drug carriers providing a prolonged gastrointestinal residence time
Kali, G.; Haddadzadegan, S.; Laffleur, F.; Bernkop-Schnürch, A.
Carbohydr. Polym., 300, 120275, 2023
Thiolated Cellulose: A Dual-Acting Mucoadhesive and Permeation-Enhancing Polymer
Kali, G.; Özkahraman, B.; Laffleur, F.; Knoll, P.; Wibel, R.; Zöller, K.; Bernkop-Schnürch, A.
Biomacromolecules, 24(11), 4880-4889, 2023
Thiolated α-cyclodextrin: The likely smallest drug carrier providing enhanced cellular uptake and endosomal escape
Kaplan, Ö.; Truszkowska, M.; Kali, G.; Knoll, P.; Blanco Massani, M.; Braun, D.E.; Bernkop-Schnürch, A.
Carbohydr. Polym., 316, 121070, 2023
Lipid-based nanoparticles: Enhanced cellular uptake via surface thiolation
Knoll, P.; Racaniello, G.F.; Laquintana, V.; Veider, F.; Saleh, A.; Seybold, A.; Denora, N.; Bernkop-Schnürch, A.
Int. J. Pharm., 635, 122753, 2023
S-Protected Thiolated Chitosan versus Thiolated Chitosan as Cell Adhesive Biomaterials for Tissue Engineering
Le-Vinh, B.; Steinbring, C.; Nguyen Le, N.M.; Matuszczak, B.; Bernkop-Schnürch, A.
ACS Appl. Mater. Interfaces, 15(34), 40304-40316, 2023
Thiolated Poly‐and Oligosaccharide‐Based Hydrogels for Tissue Engineering and Wound Healing
Noreen, S.; Bernkop‐Schnürch, A.
Advanced Functional Materials 23, S. 2310129, 2023
Peptide Antibiotic-Polyphosphate Nanoparticles: A Promising Strategy to Overcome the Enzymatic and Mucus Barrier of the Intestine
Saleh, A.; Akkus-Dagdeviren, Z.B.; Haddadzadegan, S.; Wibel, R.; Bernkop-Schnürch, A.
Biomacromolecules, 24(6), 2587-2595, 2023
Hydrophobic Ion Pairing of Small Molecules: How to Minimize Premature Drug Release from SEDDS and Reach the Absorption Membrane in Intact Form
Spleis, H.; Federer, C.; Claus, V.; Sandmeier, M.; Bernkop-Schnürch, A.
ACS Biomater. Sci. Eng., 9(3), 1450-1459, 2023
Surface design of nanocarriers: Key to more efficient oral drug delivery systems
Spleis, H.; Sandmeier, M.; Claus, V.; Bernkop-Schnürch, A.
Adv. Colloid Interface Sci., 313, 102848, 2023
PEG vs. zwitterions: How these surface decorations determine cellular uptake of lipid-based nanocarriers
Stengel, D.; Demirel, B.H.; Knoll, P.; Truszkowska, M.; Laffleur, F.; Bernkop-Schnürch, A.
J. Colloid & Interface Sci., 647, 52-64, 2023
Iminated aminoglycosides in self-emulsifying drug delivery systems: Dual approach to break down the microbial defense
To, D.; Kakar, A.; Kali, G.; Wibel, R.; Knoll, P.; Marx, F.; Bernkop-Schnürch, A.
J. Colloid & Interface Sci., 630(Pt B), 164-178, 2023
Power-Up for Mucoadhesiveness: Two Generations of Thiolated Surfactants for Enhanced Sticky Nanoemulsions
To, D.; Kali, G.; Haddadzadegan, S.; Jörgensen, A.M.; Nigl, K.; Ricci, F.; Bernkop-Schnürch, A.
ACS Biomater. Sci. Eng., 9(12), 6797-6804, 2023
Oral drug delivery: Influence of mucus on cellular interactions and uptake of lipid-based nanocarriers in Caco-2 cells
Veider, F.; Knoll, P.; Jörgensen, A.M.; Stengel, D.; Bernkop-Schnürch, A.
Acta Biomater., 167, 416-424, 2023
Oral delivery of calcitonin-ion pairs: In vivo proof of concept for a highly lipophilic counterion
Wibel, R.; Jörgensen, A.M.; Laffleur, F.; Spleis, H.; Claus, V.; Bernkop-Schnürch, A.
Int. J. Pharm., 631, 122476, 2023
Development and in vivo evaluation of nanoemulsions for oral delivery of low molecular weight heparin
Zöller, K.; Laffleur, F.; Claus, V.; Knoll, P.; To, D.; Bernkop-Schnürch, A.
J.Drug Del. Sci. Tech., 86, 104686, 2023
Nanoarchitectonics of Layer-by-Layer (LbL) coated nanostructured lipid carriers (NLCs) for Enzyme-Triggered charge reversal
Akkuş-Dağdeviren, Z.B.; Fürst, A.; Friedl, J.D.; Tribus, M.; Bernkop-Schnürch, A.
J. Colloid & Interface Sci., 629(Pt A), 541-553, 2022
Targeted Self-Emulsifying Drug Delivery Systems to Restore Docetaxel Sensitivity in Resistant Tumors
Campani, V.; Salaroglio, I.C.; Nele, V.; Kopecka, J.; Bernkop-Schnürch, A.; Riganti, C.; De Rosa, G.
Pharmaceutics, 14(2), 292, 2022
Phosphate decorated lipid-based nanocarriers providing a prolonged mucosal residence time
Efiana, N.A.; Fürst, A.; Saleh, A.; Shahzadi, I.; Bernkop-Schnürch, A.
Int. J. Pharm., 625, 122096, 2022
Charge-reversal nanoemulsions: A systematic investigation of phosphorylated PEG-based surfactants
Federer, C.; Claus, V.; Hock, N.; Friedl, J.D.; Wibel, R.; Bernkop-Schnürch, A.
Int. J. Pharm., 613, 121438, 2022
Preparation and Evaluation of Charge Reversal Solid Lipid Nanoparticles
Federer, C.; Spleis, H.V.; Summonte, S.; Friedl, J.D.; Wibel, R.; Bernkop-Schnürch, A.
J. Pharm. Sci., 111(8), 2270-2279, 2022
Reactive oxygen species (ROS) in colloidal systems: Are 'PEG-free' surfactants the answer?
Friedl, D.J.; Wibel, R.; Akkuş-Dağdeviren, Z.B.; Bernkop-Schnürch, A.
J. Colloid & Interface Sci., 616, 571-583, 2022
Replacing PEG-surfactants in self-emulsifying drug delivery systems: Surfactants with polyhydroxy head groups for advanced cytosolic drug delivery
Friedl, J.D.; Jörgensen, A.M.; Nguyen Le, N.M.; Steinbring, C.; Bernkop-Schnürch, A.
Int. J. Pharm., 618, 121633, 2022
SEDDS-loaded mucoadhesive fiber patches for advanced oromucosal delivery of poorly soluble drugs
Friedl, J.D.; Walther, M.; Vestweber, P.K.; Wächter, J.; Knoll, P.; Jörgensen, A.M.; Bernkop-Schnürch, A.; Windbergs. M.
J. Control. Rel., 348, 692-705, 2022
Entirely S-protected thiolated hydroxyethylcellulose: Design of a dual cross-linking approach for hydrogels
Fürst, A.; Shahzadi, I.; Burcu Akkuş-Dağdeviren, Z.; Kali, G.; Hupfauf, A.; Gust, R.; Bernkop-Schnürch,A.
Eur. J. Pharm. Biopharm., 181, 292-299, 2022
Thiolated 2-Methyl-β-Cyclodextrin as a Mucoadhesive Excipient for Poorly Soluble Drugs: Synthesis and Characterization
Grassiri, B.; Cesari, A.; Balzano, F.; Migone, C.; Kali, G.; Bernkop-Schnürch, A.; Uccello-Barretta, G.; Zambito, Y.; Piras, A.M.
Polymers (Basel), 14(15), 3170, 2022
Thiolated Hydroxypropyl-β-cyclodextrin: A Potential Multifunctional Excipient for Ocular Drug Delivery
Grassiri, B.; Knoll, P.; Fabiano, A.; Piras, A.M.; Zambito, Y.; Bernkop-Schnürch, A.
Int. J. Mol. Sci., 23(5), 2612, 2022
Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers
Haddadzadegan, S.; Dorkoosh, F.; Bernkop-Schnürch, A.
Adv. Drug Del. Rev., 182, 114097, 2022
Thiolated Nanoparticles for Biomedical Applications: Mimicking the Workhorses of Our Body
Hock, N.; Racaniello, G.F.; Aspinall, S.; Denora, N.; Khutoryanskiy, V.V.; Bernkop-Schnürch, A.
Adv. Sci. (Weinh), 9(1), e2102451, 2022
Emerging technologies to increase gastrointestinal transit times of drug delivery systems
Kali, G.; Knoll, P.; Bernkop-Schnürch, A.
J. Control. Rel., 346, 289-299, 2022
Preparation and detailed characterization of the thiomer chitosan-cysteine as a suitable mucoadhesive excipient for nasal powders
Kiss, T.; Ambrus, R.; Abdelghafour, M.M.; Zeiringer, S.; Selmani, A.; Roblegg, E.; Budai-Szűcs, M.; Janovák, L.; Lőrinczi, B.; Deák, Á.; Bernkop-Schnürch, A.; Katona, G.
Int. J. Pharm., 626, 122188, 2022
Charge converting nanostructured lipid carriers containing a cell-penetrating peptide for enhanced cellular uptake
Knoll, P.; Hörmann, N.; Nguyen Le, N.M.; Wibel, R.; Gust, R.; Bernkop-Schnürch, A.
J. Colloid & Interface Sci., 628(Pt A), 463-475, 2022
Polyaminated pullulan, a new biodegradable and cationic pullulan derivative for mucosal drug delivery
Le, N.N.; Le-Vinh, B.; Friedl, .JD.; Jalil, A.; Kali, G.; Bernkop-Schnürch, A.
Carbohydr. Polym., 282, 119143, 2022
Alkaline Phosphatase: A Reliable Endogenous Partner for Drug Delivery and Diagnostics
Le‐Vinh, B.; Akkuş‐Dağdeviren, Z.B.; Le, N.M.N.; Nazir, I.; Bernkop‐Schnürch,
Adv. Ther., 2100219, 2022
Charge-Converting Nanoemulsions as Promising Retinal Drug and Gene Delivery Systems
Nguyen Le, N.M.; Zsák, S.; Le-Vinh, B.; Friedl, J.D.; Kali, G.; Knoll, P.; Seitter, H.W.; Koschak, A., Bernkop-Schnürch, A.
ACS Appl. Mater. Interfaces, 14(39), 44981-44991, 2022
Thiolation of non-ionic surfactants for the development of lipid-based mucoadhesive drug delivery systems
Racaniello, G.F.; Knoll, P.; Jörgensen, A.M.; Arduino, I.; Laquintana, V.; Lopedota, A.A.; Bernkop-Schnürch, A.; Denora, N.
Eur. J. Pharm. Biopharm., 179, 95-104, 2022
Chitosan – Polyphosphate nanoparticles for a targeted drug release at the absorption membrane
Saleh, A.; Akkuş-Dağdeviren, Z.B.; Friedl, J.D.; Knoll, P.; Bernkop-Schnürch, A.
Heliyon, 8(9), e10577, 2022
Thiolated Chitosan Conjugated Liposomes for Oral Delivery of Selenium Nanoparticles
Selmani, A.; Seibert, E.; Tetyczka, C.; Kuehnelt, D.; Vidakovic, I.; Kornmueller, K.; Absenger-Novak, M.; Radatović, B.; Vinković Vrček, I.; Leitinger, G.; Fröhlich, E.; Bernkop-Schnürch, A.; Roblegg, E.; Prassl, R.
Pharmaceutics, 14(4), 803, 2022
Design of nanostructured lipid carriers and solid lipid nanoparticles for enhanced cellular uptake
Veider, F.; Akkuş-Dağdeviren, Z.B.; Knoll, P.; Bernkop-Schnürch, A.
Int. J. Pharm., 624, 122014, 2022
Synthesis and evaluation of sulfosuccinate-based surfactants as counterions for hydrophobic ion pairing
Wibel, R.; Knoll, P.; Le-Vinh, B.; Kali, G.; Bernkop-Schnürch, A.
Acta Biomater., 144, 54-66, 2022
Development and In Vitro Characterization of Transferrin-Decorated Nanoemulsion Utilizing Hydrophobic Ion Pairing for Targeted Cellular Uptake
Zaichik, A.; Steinbring, C.; Friedl, J.; Bernkop-Schnürch, A.
J.Pharm. Inn., 17, 690–700, 2022
Digestion of lipid excipients and lipid-based nanocarriers by pancreatic lipase and pancreatin
Zöller, K.; To, D.; Knoll, P.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 176, 32-42, 2022
Intraoral Drug Delivery: Three Ways to Prolong Mucosal Residence Time
Bernkop-Schnürch, A.
IPEC Europe Excipient Conference 2021, 2021
Mucoadhesive Polymers: Gateway to Innovative Drug Delivery
Yaqoob, M.; Jalil, A.; Bernkop-Schnürch, A.
Modeling and Control of Drug Delivery Systems, 2021
Charge reversal self-emulsifying drug delivery systems: A comparative study among various phosphorylated surfactants
Akkuş-Dağdeviren, Z.B.; Wolf, J.D.; Kurpiers, M.; Shahzadi, I.; Steinbring, C.; Bernkop-Schnürch, A.
J. Colloid & Interface Sci., 589, 532-544, 2021
Thiolated cyclodextrins: Mucoadhesive and permeation enhancing excipients for ocular drug delivery
Asim, M.H.; Ijaz, M.; Mahmood, A.; Knoll, P.; Jalil, A.; Arshad, S.; Bernkop-Schnürch, A.
Int. J. Pharm., 599, 120451, 2021
Imine bond formation as a tool for incorporation of amikacin in self-emulsifying drug delivery systems (SEDDS)
Dizdarević, A.; Marić, M.; Shahzadi, I.; Ari Efiana, N.; Matuszczak, B.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 162, 82-91, 2021
Thiolated Chitosans: A Multi-talented Class of Polymers for Various Applications
Federer, C.; Kurpiers, M.; Bernkop-Schnürch, A.
Biomacromolecules, 22, 24-56, 2021
Solidification of self-emulsifying drug delivery systems (SEDDS): Impact on storage stability of a therapeutic protein
Friedl, J.D.; Jörgensen, A.M.; Le-Vinh, B.; Braun, D.E.; Tribus, M.; Bernkop-Schnürch, A.
J. Colloid & Interface Sci., 584, 684-697, 2021
Bioinert, Stealth or Interactive: How Surface Chemistry of Nanocarriers Determines Their Fate In Vivo
Friedl, J.D.; Nele, V.; De Rosa, G.; Bernkop-Schnürch, A.
Adv. Funct. Mat., 31, 2103347, 2021
Strategies to prolong the residence time of drug delivery systems on ocular surface
Grassiri, B.; Zambito, Y.; Bernkop-Schnürch, A.
Adv. Colloid Interf. Sci., 288, 102342, 2021
Thiolated pectins: In vitro and ex vivo evaluation of three generations of thiomers
Knoll, P.; Le, N.N.; Wibel, R.; Baus, R.A.; Kali, G.; Asim, M.H.; Bernkop-Schnürch, A.
Acta Biomater., 135,139-149, 2021
Lysine-Based Biodegradable Surfactants: Increasing the Lipophilicity of Insulin by Hydrophobic Ion Paring
Kurpiers, M.; Wolf, J.D.; Spleis, H.; Steinbring, C.; Jörgensen, A.M.; Matuszczak, B.; Bernkop-Schnürch, A.
J. Pharm. Sci., 110, 124-134, 2021
Mucolytic self-emulsifying drug delivery systems (SEDDS) containing a hydrophobic ion-pair of proteinase
Lam, H.T.; Le, N.N.; Phan, T.N.Q.; Bernkop-Schnürch, A.
Eur. J. Pharm. Sci., 162, 105658, 2021
Mucoadhesive properties of polyacrylates:Structure – Function relationship
Lam, H.T.; Zupancic, O.; Laffleur, F.; Bernkop-Schnürch, A.
Int. J. Adh. Adhs., 107, 102857, 2021
Polyphosphate coatings: A promising strategy to overcome the polycation dilemma
Le, N.N.; Steinbring, C.; Le-Vinh, B.; Jalil, A.; Matuszczak, B.; Bernkop-Schnürch, A.
J. Colloid & Interface Sci., 587, 279-289, 2021
Size shifting of solid lipid nanoparticle system triggered by alkaline phosphatase for site specific mucosal drug delivery
Le-Vinh, B.; Steinbring, C.; Wibel, R.; Friedl, J.D.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 163, 109-119, 2021
Impact of Bile Salts and a Medium Chain Fatty Acid on the Physical Properties of Self-Emulsifying Drug Delivery Systems
Lupo, N.; Steinbring, C.; Friedl, J.D.; Le-Vinh, B.; Bernkop-Schnürch, A.
Drug Dev. Ind. Pharm., 47, 22-35, 2021
Spray-dried mucoadhesive microparticles based on S-protected thiolated hydroxypropyl-β-cyclodextrin for budesonide nasal delivery
Racaniello, G.F.; Laquintana, V.; Summonte, S.; Lopedota, A.; Cutrignelli, A.; Lopalco, A.; Franco, M.; Bernkop-Schnürch, A.; Denora, N.
Int. J. Pharm., 603, 120728, 2021
Nanostructured Lipid Carriers (NLCs) for Oral Peptide Drug Delivery: About the Impact of Surface Decoration
Shahzadi, I.; Fürst, A.; Knoll, P.; Bernkop-Schnürch, A.
Pharmaceutics, 13, 1312, 2021
Zeta potential changing nanoemulsions based on a simple zwitterion
Sharifi, F.; Jahangiri, M.; Nazir, I.; Asim, M.H.; Ebrahimnejad, P.; Hupfauf, A.; Gust, R.; Bernkop-Schnürch, A.
J. Colloid & Interface Sci., 585, 126-137, 2021
Thiolated polymeric hydrogels for biomedical application: Cross-linking mechanisms
Summonte, S.; Racaniello, G.F.; Lopedota, A.; Denora, N.; Bernkop-Schnürch, A.
J. Control. Rel., 330, 470-482, 2021
Overcoming the Mucosal Barrier: Tetraether Lipid-Stabilized Liposomal Nanocarriers Decorated with Cell-Penetrating Peptides Enable Oral Delivery of Vancomycin
Uhl, P.; Sauter, M.; Hertlein, T.; Witzigmann, D.; Laffleur, F.; Hofhaus, G.; Fidelj, V.; Tursch, A.; Özbek, S.; Hopke, E.; Haberkorn, U.; Bernkop-Schnürch, A.; Ohlsen, K.; Fricker, G.; Mier, W.
Adv. Ther., 4, 2000247, 2021
Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network
Vinarov, Z.; Abrahamsson, B.; Artursson, P.; Batchelor, H.; Berben, P.; Bernkop-Schnürch, A.; Butler, J.; Ceulemans, J.; Davies, N.; Dupont, D.; Flaten, G.E.; Fotaki, N.; Griffin, B.T.; Jannin, V.; Keemink, J.; Kesisoglou, F.; Koziolek, M.; Kuentz, M.; Mackie, A.; Meléndez-Martínez, A.J.; McAllister, M.; Müllertz, A.; O'Driscoll, C.M.; Parrott, N.; Paszkowska, J.; Pavek, P.; Porter, C.J.H.; Reppas, C.; Stillhart, C.; Sugano, K.; Toader, E.; Valentová, K.; Vertzoni, M.; De Wildt, S.N.; Wilson, C.G.; Augustijns, P.
Adv. Drug Del. Rev., 171, 289-331, 2021
In Vitro Investigation of Thiolated Chitosan Derivatives as Mucoadhesive Coating Materials for Solid Lipid Nanoparticles
Wibel, R.; Braun, D.E.; Hämmerle, L.; Jörgensen, A.M.; Knoll, P.; Salvenmoser, W.; Steinbring, C.; Bernkop-Schnürch, A.
Biomacromolecules, 22, 3980-3991, 2021
Mucoadhesive Polymers: Gateway to Innovative Drug Delivery
Yaqoob, M.; Jalil, A.; Bernkop-Schnürch, A.
Mod. Contr. Drug Del. Syst. 2021, 351-383, 2021
Intraoral Drug Delivery: Three Ways to Prolong Mucosal Residence Time
Bernkop-Schnürch, A.
IPEC Europe Excipient Conference 2020, 2020
Vaginal delivery systems containing selective estrogen receptor modulator (SERM) and uses thereof
Ceva, V.; Goldstein, S. R.; Levinson, S. L.; Thompson, D. D.; Bernkop-Schnürch, A.; Nardin, I.
US Patent 10,857,127, 2020
S-Protected thiolated nanostructured lipid carriers exhibiting improved mucoadhesive properties
Arshad, S.; Rehman, M.U.; Hussain, A.M.; Nazir, I.; Shahzadi, I.; Mousli, M.; Bernkop-Schnürch, A.
Int. J. Pharm., 587, 119690, 2020
Per-6-Thiolated Cyclodextrins: A Novel Type of Permeation Enhancing Excipients for BCS Class IV Drugs
Asim, M.H.; Nazir, I.; Jalil, A.; Laffleur, F.; Matuszczak, B.; Bernkop-Schnürch, A.
ACS Appl. Mater. Interfaces, 12(7), 7942-7950, 2020
S-protected thiolated hyaluronic acid: In-situ crosslinking hydrogels for 3D cell culture scaffold
Asim, M.H.; Silberhumer, S.; Shahzadi, I.; Jalil, A.; Matuszczak, B.; Bernkop-Schnürch, A.
Carbohydr. Polym., 237, 116092, 2020
Strategies for improved hair binding: Keratin fractions and the impact of cationic substructures
Baus, R.A.; Leichner, C.; Steinbring, C.; Bernkop-Schnürch, A.
Int. J. Biol. Macromol., 160, 201-211, 2020
Storage stability of proteins in a liquid-based formulation: Liquid vs. solid self-emulsifying drug delivery
Etezadi, H.; Maleki, A.; Friedl, J.D.; Bernkop-Schnürch, A.
Int. J. Pharm., 590, 119918, 2020
Cellular uptake of self-emulsifying drug-delivery systems: polyethylene glycol versus polyglycerol surface
Friedl, J.D.; Steinbring, C.; Zaichik, S.; Le, N.N.; Bernkop-Schnürch, A.
Nanomedicine (Lond), 15(19), 1829-1841, 2020
Tetradeca-thiolated cyclodextrins: Highly mucoadhesive and in-situ gelling oligomers with prolonged mucosal adhesion
Hussain, A.M.; Nazir, I.; Jalil, A.; Matuszczak, B.; Bernkop-Schnürch, A.
Int. J. Pharm., 577, 119040, 2020
Hydrophobic ion pairing of a GLP-1 analogue for incorporating into lipid nanocarriers designed for oral delivery
Ismail, R.; Phan, T.N.Q.; Laffleur, F.; Csóka, I.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 152, 10-17, 2020
Self-emulsifying drug delivery systems containing hydrophobic ion pairs of polymyxin B and agaric acid: A decisive strategy for enhanced antimicrobial activity
Jalil, A.; Asim, M.H.; Nazir, I.; Matuszczak, B.; Bernkop-Schnürch, A.
J. Mol. Liquids, 311, 113298, 2020
Thiolated PVP-Amphotericin B Complexes: An Innovative Approach toward Highly Mucoadhesive Gels for Mucosal Leishmaniasis Treatment
Jalil, A.; Asim, M.H.; Shahzadi, I.; Khan, M.; Matuszczak, B.; Bernkop-Schnürch, A.
Biomacromolecules, 21(9), 3658-3667, 2020
A gellan gum derivative as in-situ gelling cationic polymer for nasal drug delivery
Jelkmann, M.; Leichner, C.; Zaichik, S.; Laffleur, F.; Bernkop-Schnürch, A.
Int. J. Biol. Macromol., 158, 1037-1046, 2020
Cosolvents in Self-Emulsifying Drug Delivery Systems (SEDDS): Do They Really Solve Our Solubility Problems?
Jörgensen, A.M.; Friedl, J.D.; Wibel, R.; Chamieh, J.; Cottet, H.; Bernkop-Schnürch, A.
Mol Pharm., 17(9), 3236-3245, 2020
Zeta potential changing nanoemulsions based on phosphate moiety cleavage of a PEGylated surfactant
Kurpiers, M.; Wolf, J.D.; Steinbring, C.; Zaichik, S.; Bernkop-Schnürch, A.
J. Mol. Liquids, 316, 113868, 2020
Grafting of wool fibers through disulfide bonds: An advanced application of S-protected thiolated starch
Le, N.N.; Steinbring, C.; Matuszczak, B.; Baus, .RA.; Tribus, M.; Pham, T.; Bechtold, T.; Bernkop-Schnürch, A.
Int. J. Biol. Macromol., 147, 473-481, 2020
Composite nanocellulose-based hydrogels with spatially oriented degradation and retarded release of macromolecules
Maestri, C.A.; Motta, A.; Moschini, L.; Bernkop-Schnürch, A.; Baus, R.A.; Lecca, P.; Scarpa, M.
J. Biomed. Mat. Res. A., 108(7), 1509-1519, 2020
Self-Emulsifying Drug Delivery Systems: Hydrophobic Drug Polymer Complexes Provide a Sustained Release in Vitro
Malkawi, A.; Jalil, A.; Nazir, I.; Matuszczak, B.; Kennedy, R.; Bernkop-Schnürch, A.
Mol Pharm., 17(10), 3709-3719, 2020
Self-emulsifying drug delivery systems: About the fate of hydrophobic ion pairs on a phospholipid bilayer
Nazir, I.; Ghezzi, M.; Asim, M.H.; Phan, T.N.Q
J. Mol. Liquids, 312, 113382, 2020
Hydrophobic H-bond pairing: A novel approach to improve membrane permeability
Nazir, I.; Shahzadi, I.; Jalil, A.; Bernkop-Schnürch, A.
Int. J. Pharm., 573, 118863, 2020
Thiolated chitosans: Are Cys-Cys ligands key to the next generation?
Netsomboon, K.; Jalil, A.; Laffleur, F.; Hupfauf, A.; Gust, R.; Bernkop-Schnürch, A.
Carbohydr. Polym., 242, 116395, 2020
Diaminated Starch: A Competitor of Chitosan with Highly Mucoadhesive Properties due to Increased Local Cationic Charge Density
Nouri, A.; Jelkmann, M.; Khoee, S.; Bernkop-Schnürch, A.
Biomacromolecules, 21(2), 999-1008, 2020
Development and In Vitro Evaluation of Stearic Acid Phosphotyrosine Amide as New Excipient for Zeta Potential Changing Self-Emulsifying Drug Delivery Systems
Prüfert, F.; Fischer, F.; Leichner, C.; Zaichik, S.; Bernkop-Schnürch, A.
Pharm. Res., 37(4), 79, 2020
Synthesis and in vitro characterization of a preactivated thiolated acrylic acid/acrylamide-methylpropane sulfonic acid copolymer as a mucoadhesive sprayable polymer
Prüfert, F.; Hering, U.; Zaichik, S.; Le, N.N.; Bernkop-Schnürch, A.
Int. J. Pharm., 583, 119371, 2020
Less Reactive Thiol Ligands: Key towards Highly Mucoadhesive Drug Delivery Systems
Shahzadi, I.; Fürst, A.; Akkus-Dagdeviren, Z.B.; Arshad, S.; Kurpiers, M.; Matuszczak, B.; Bernkop-Schnürch, A.
Polymers, 12(6), E1259. Basel, 2020
Lipophilic Arginine Esters: The Gateway to Preservatives without Side Effects
Shahzadi, I.; Jalil, A.; Asim, M.H.; Hupfauf, A.; Gust, R.; Nelles, P.A.; Knabl, L.; Bernkop-Schnürch, A.
Mol Pharm., 17(8), 3129-3139, 2020
About the Impact of Superassociation of Hydrophobic Ion Pairs on Membrane Permeability
Shahzadi, I.; Nazir, I.; Phan, T.N.Q.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 151, 1-8, 2020
Zeta potential changing nanoemulsions based on a simple zwitterion
Sharifi, F.; Jahangiri, M.; Nazir, I.; Hussain, M.; Pedram Ebrahimnejad, P.; Hupfauf, A.; RonaldGust, R.; Bernkop-Schnürch, A.
J. Colloid & Interface Sci., 585, 126-137, 2020
Hydrophobic ion pairing (HIP) of (poly)peptide drugs: Benefits and drawbacks of different preparation methods
Wibel, R.; Friedl, J.D.; Zaichik, S.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 151, 73-80, 2020
Characterization of an amino acid based biodegradable surfactant facilitating the incorporation of DNA into lipophilic delivery systems
Wolf, J.D.; Kurpiers, M.; Baus, R.A.; Götz, R.X.; Griesser, J.; Matuszczak, B.; Bernkop-Schnürch, A.
J. Colloid Interface Sci., 566, 234-241, 2020
Phosphorylated PEG-emulsifier: Powerful tool for development of zeta potential changing self-emulsifying drug delivery systems (SEDDS)
Wolf, J.D.; Kurpiers, M.; Götz, R.X.; Zaichik, S.; Hupfauf, A.; Baecker, D.; Gust, R.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 150, 77-86, 2020
Zeta Potential Changing Nanoemulsions: Impact of PEG-corona on Phosphate Cleavage
Zaichik, S.; Steinbring, C.; Jelkmann, M.; Bernkop-Schnürch, A.
Int. J. Pharm., 581, 119299, 2020
Advanced nanoemulsions: Key to high bioavailability of class 3 drugs
Bernkop-Schnürch, A.
BioTech Pharma Summit – Drug Delivery & Formulation 2019, 2019
Zeta Potential Changing Polyphosphate Nanoparticles: A promising approach to overcome the mucus and epithelial barrier
Akkus, Z.B.; Nazir, I.; Jalil, A.; Tribus, M.; Bernkop-Schnürch, A.
Pharm., 16, 2817-2825, 2019
Mucoadhesive S-protected thiolated cyclodextrin-iodine complexes: a promising strategy to prolong mucosal residence time of iodine
Asim, M.H.; Jalil, A.; Shahzadi, I.; Khan, M.; Matuszczak, B.; Bernkop-Schnürch, A.
Future Microbiol., 14, 411-424, 2019
Mucoadhesive hydrogels for buccal drug delivery: In vitro- in vivo correlation study
Baus, R.; Zahir-Jouzdani, F., Dünnhaupt, S.; Atyabi, F.; Bernkop-Schnürch, A.
J. Pharm. Biopharm., 142, 498-505, 2019
In Vitro-in Vivo Correlation of Mucoadhesion Studies on Buccal Mucosa
Baus, R.A.; Haug, M.F.; Leichner, C.; Jelkmann, M.; Bernkop-Schnürch, A.
Pharm., 16, 2719-2727, 2019
Self-emulsifying drug delivery systems (SEDDS) - The splendid comeback of an old technology
Bernkop-Schnürch, A.; Müllertz, A.; Rades, T.
Drug Del. Rev., 142, 1-2, 2019
Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems
Boyd, B.J.; Bergström, C.A.S.; Vinarov, Z.; Kuentz, M.; Brouwers, J.; Augustijns, P.; Brandl, M.; Bernkop-Schnürch, A.; Shrestha, N.; Préat, V.; Müllertz, A.; Bauer-Brandl, A.; Jannin, V.
J. Pharm. Sci., 137, 104967, 2019
Development and in vitro characterization of an oral self-emulsifying delivery system (SEDDS) for rutin fatty ester with high mucus permeating properties
Cardona, M.I.; Nguyen Le, N.M.; Zaichik, S.; Aragón, D.M.; Bernkop-Schnürch, A.
J. Pharm., 562, 180-186, 2019
Imine bond formation: A novel concept to incorporate peptide drugs in self-emulsifying drug delivery systems (SEDDS)
Dizdarević, A.; Ari Efiana, N.; Phan, T.N.Q.; Matuszczak, B.; Bernkop Schnürch, A.
J. Pharm. Biopharm., 142, 92-100, 2019
Improved intestinal mucus permeation of vancomycin via incorporation into nanocarrier containing papain-palmitate
Efiana, N.A.; Dizdarević, A.; Huck, C.W.; Bernkop-Schnürch, A.
Pharm. Sci., 108, 3329-3339, 2019
Entirely S-Protected Thiolated Silicone: A Novel Hydrophobic Mucoadhesive and Skin Adhesive
Fürst, A.; Baus, R.A.; Lupo, N.; Bernkop-Schnürch, A.
Pharm. Sci., 108, 2887-2894, 2019
Highly mucus permeating and zeta potential changing self-emulsifying drug delivery systems: A potent gene delivery model for causal treatment of cystic fibrosis
Griesser, J.; Hetényi, G.; Federer, C.; Steinbring, C.; Ellemunter, H.; Niedermayr, K.; Bernkop-Schnürch, A.
J. Pharm., 557, 124-134, 2019
S-protected gellan gum: Decisive approach towards mucoadhesive antimicrobial vaginal films
Jalil, A.; Asim, M.H.; Le, N.N.; Laffleur, F.; Matuszczak, B.; Tribus, M.; Bernkop-Schnürch, A.
J. Biol. Macromol., 130, 148-157, 2019
Self-emulsifying drug delivery systems comprising chlorohexidine and alkyl-EDTA: A novel approach for augmented antimicrobial activity
Jalil, A.; Hussain, M.A.; Akkus, Z.B.; Schoenthaler, M.; Matuszczak, B.; Bernkop-Schnürch, A.
Mol. Liquids, 295, 111649, 2019
Cationic starch derivatives as mucoadhesive and soluble excipients in drug delivery
Jelkmann, M.; Leichner, C.; Menzel, C.; Kreb, V.; Bernkop-Schnürch, A.
J. Pharm., 570, 118664, 2019
Self-emulsifying drug delivery systems and cationic surfactants: do they potentiate each other in cytotoxicity?
Lam, H.T.; Le-Vinh, B.; Phan, T.N.Q.; Bernkop-Schnürch, A.
Pharm. Pharmacol., 71, 156-166, 2019
Thiolated hydroxypropyl-β-cyclodextrin as mucoadhesive excipient for oral delivery of budesonide in liquid paediatric formulation
Laquintana, V.; Asim, M.H.; Lopedota, A.; Cutrignelli, A.; Lopalco, A.; Franco, M.; Bernkop-Schnürch, A.; Denora, N.
J. Pharm., 572, 118820, 2019
Chitosan based micelle with zeta potential changing property for effective mucosal drug delivery
Le-Vinh B, Le, N.N.; Nazir, I.; Matuszczak, B.; Bernkop-Schnürch, A.
J. Biol. Macromol., 133, 647-655, 2019
In vitro evaluation of a self-emulsifying drug delivery system (SEDDS) for nasal administration of dimenhydrinate
Leichner, C.; Baus, R.A.; Jelkmann, M.; Plautz, M.; Barthelmes, J.; Dünnhaupt, S.; Bernkop-Schnürch, A.
Drug Deliv. Transl. Res. 9(5), 945-955, 2019
Thiolated polymers: Bioinspired polymers utilizing one of the most important bridging structures in nature
Leichner, C.; Jelkmann, M.; Bernkop-Schnürch, A.
Drug Del. Rev., 151-152, 191-221, 2019
Intestinal enzyme delivery: Chitosan/tripolyphosphate nanoparticles providing a targeted release behind the mucus gel barrier
Leichner, C.; Jelkmann, M.; Prüfert, F.; Laffleur, F.; Bernkop-Schnürch, A.
J. Pharm. Biopharm., 144, 125-131, 2019
Reactive keratin derivatives: A promising strategy for covalent binding to hair
Leichner, C.; Steinbring, C.; Baus, R.A.; Baecker, D.; Gust, R.; Bernkop-Schnürch, A.
Colloid Interface Sci., 534, 533-541, 2019
N-Hydroxysulfosuccinimide Esters versus Thiomers: A Comparative Study Regarding Mucoadhesiveness
Leichner, C.; Wulz, P.; Baus, R.A.; Menzel, C.; Götzfried, S.K.; Gust, R.; Bernkop-Schnürch, A.
Pharm., 16, 1211-1219, 2019
Self-emulsifying drug delivery systems: In vivo evaluation of their potential for oral vaccination
Lupo, N,; Tkadlečková, V.N.; Jelkmann, M.; Laffleur, F.; Hetényi, G.; Kubová, K.; Bernkop-Schnürch, A.
Acta Biomater., 94, 425-434, 2019
In vitro evaluation of intravesical mucoadhesive self-emulsifying drug delivery systems
Lupo, N.; Jalil, A.; Nazir, I.; Gust, R.; Bernkop-Schnürch, A.
J. Pharm., 564, 180-187, 2019
SEDDS: A game changing approach for the oral administration of hydrophilic macromolecular drugs
Mahmood, A.; Bernkop-Schnürch, A.
Drug Del. Rev., 142, 91-101, 2019
Covalently binding mucoadhesive polymers: N-hydroxysuccinimide grafted polyacrylates
Menzel, C, Hauser, M.; Frey, A.; Jelkmann, M.; Laffleur, F.; Götzfried, S.K.; Gust, R.; Bernkop-Schnürch, A.
J. Pharm. Biopharm., 139, 161-167, 2019
Self-emulsifying drug delivery systems: Impact of stability of hydrophobic ion pairs on drug release
Nazir, I.; Asim, M.H.; Dizdarević, A.; Bernkop-Schnürch, A.
J. Pharm., 561, 197-205, 2019
Zeta potential changing self-emulsifying drug delivery systems: A promising strategy to sequentially overcome mucus and epithelial barrier
Nazir, I.; Fürst, A.; Lupo, N.; Hupfauf, A.; Gust, R.; Bernkop-Schnürch, A.
J. Pharm. Biopharm., 144, 40-49, 2019
Oral delivery of non-viral nucleic acid-based therapeutics - do we have the guts for this?
O'Driscoll, C.M.; Bernkop-Schnürch, A.; Friedl, J.D.; Préat, V.; Jannin, V.
J. Pharm. Sci., 133, 190-204, 2019
Oral self-emulsifying delivery systems for systemic administration of therapeutic proteins: Science fiction?
Phan, T.N.Q.; Le-Vinh. ; Efiana, N.A.; Bernkop-Schnürch, A.
J. Drug Targ., 19, 1-27. 27, 1017-1024, 2019
Hydrophobic ion-pairs and lipid-based nanocarrier systems: The perfect match for delivery of BCS class 3 drugs
Phan, T.N.Q.; Shahzadi, I.; Bernkop-Schnürch, A.
Control. Rel., 304, 146-155, 2019
Arginine-based cationic surfactants: Biodegradable auxiliary agents for the formation of hydrophobic ion pairs with hydrophilic macromolecular drugs
Shahzadi, I.; Asim, M.H.; Dizdarević, A.; Wolf, J.D.; Kurpiers, M.; Matuszczak, B.; Bernkop-Schnürch, A.
Colloid Interface Sci., 552, 287-294, 2019
Mucoadhesive micro-composites: Chitosan coated halloysite nanotubes for sustained drug delivery
Sharif, S.; Abbas, G.; Hanif, M.; Bernkop-Schnürch, A.; Jalil, A.; Yaqoob, M.
Colloids Surf. B Biointerfaces, 184, 110527, 2019
Zeta potential changing self-emulsifying drug delivery systems utilizing a novel Janus-headed surfactant: A promising strategy for enhanced mucus permeation
Sharifi, F.; Nazir, I.; Hussain, M.A.; Jahangiri, M.; Ebrahimnejad, P.; Barbara Matuszczak f, Bernkop-Schnürch, A.
Mol. Liquids, 291, 111285, 2019
Lipids and polymers in pharmaceutical technology: Lifelong companions
Siepmann, J.; Faham, A.; Clas, S.D.; Boyd, B.J.; Jannin, V.; Bernkop-Schnürch, A.; Zhao, H.; Lecommandoux, S.; Evans, J.C.; Allen, C.; Merkel, O.M.; Costabile, G.; Alexander, M.R.; Wildman, R.D.; Roberts, C.J.; Leroux, J.C.
J. Pharm., 558, 128-142, 2019
Development and in vitro evaluation of a self-emulsifying drug delivery system (SEDDS) for oral vancomycin administration
Zaichik, S.; Steinbring, C.; Caliskan, C.; Bernkop-Schnürch, A.
J. Pharm., 554, 125-133, 2019
S-protected thiolated cyclodextrins as mucoadhesive oligomers for drug delivery
Asim, M.H.; Moghadam, A.; Ijaz, M.; Mahmood, A.; Götz, R.X.; Matuszczak, B.; Bernkop-Schnürch, A.
J. Colloid Interface Sci., 531, 261-268, 2018
Anhydrous Thiomers: Strategy For Enhanced Mucoadhesion
Baus, R.; Innerhofer, J.; Rohrer, J.; Lupo, N.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 129, 273-281, 2018
Strategies to overcome the polycation dilemma in drug delivery
Bernkop-Schnürch, A
Adv. Drug Del. Rev., 136-137, 62-72, 2018
Do drug release studies from SEDDS make any sense?
Bernkop-Schnürch, A.; Jalil, A.
J. Control. Rel., 271, 55-59, 2018
Impact of different hydrophobic ion pairs of octreotide on its oral bioavailability in pigs
Bonengel, S.; Jelkmann, M.; Abdulkarim, M.; Gumbleton, M.; Reinstadler, V.; Oberacher, H.; Prüfert, F.; Bernkop-Schnürch, A.
J. Control. Rel., 273, 21-29, 2018
Mucus permeating self-emulsifying drug delivery systems (SEDDS): About the impact of mucolytic enzymes
Efiana, N.A.; Phan, T.N.Q.; Wicaksono, A.J.; Bernkop-Schnürch, A.
Colloids Surf. B Biointerfaces, 161, 228-235, 2018
Mucoadhesive self-emulsifying delivery systems for ocular administration of econazole
Elbahwy, I.A.; Lupo, N.; Ibrahim, H.M.; Ismael, HR.; Kasem, A.A.; Caliskan, C.; Matuszczak, B.; Bernkop-Schnürch, A.
Int. J. Pharm., 541, 72-80, 2018
Development of a nasal spray containing xylometazoline hydrochloride and iota-carrageenan for the symptomatic relief of nasal congestion caused by rhinitis and sinusitis
Graf, C.; Bernkop-Schnürch, A.; Egyed, A.; Koller, C.; Prieschl-Grassauer, E.; Morokutti-Kurz, M.
Int. J. Gen. Med., 11, 275-283, 2018
Thiolated Hyaluronic Acid as Versatile Mucoadhesive Polymer
Griesser, J.; Hetényi, G.; Bernkop-Schnürch, A.
Polymers, 10, (1) 243, 2018
Self-emulsifying peptide drug delivery systems: How to make them highly mucus permeating
Griesser, J.; Hetényi, G.; Kadas, H.; Demarne, F.; Jannin, V.; Bernkop-Schnürch, A.
Int. J. Pharm., 538, 159-166, 2018
Amikacin-containing self-emulsifying delivery systems via pulmonary administration for treatment of bacterial infections of cystic fibrosis patients
Hetényi, G.; Griesser, J.; Fontana, S.; Gutierrez, A,M.; Ellemunter, H.; Niedermayr, K.; Szabó, P.; Bernkop-Schnürch, A.
Nanomedicine (Lond)., 13(7), 717-732, 2018
Synthesis and Characterization of Thiolated PVP-Iodine Complexes: Key to Highly Mucoadhesive Antimicrobial Gels
Jalil, A.; Matuszczak, B.; Nguyen Le, N.M.; Mahmood, A.; Laffleur, F.; Bernkop-Schnürch, A.
Mol. Pharm., 15(8), 3527-3534, 2018
New perspectives of starch: Synthesis and in vitro assessment of novel thiolated mucoadhesive derivatives
Jelkmann, M.; Bonengel, S.; Menzel, C.; Markovic, S.; Bernkop-Schnürch, A.
Int. J. Pharm., 546, 70-77, 2018
Chitosan: The One and Only? Aminated Cellulose as an Innovative Option for Primary Amino Groups Containing Polymers
Jelkmann, M.; Menzel, C.; Baus, R.A.; Ausserhofer, P.; Baecke, D.; Gust, R.; Bernkop-Schnürch, A.
Biomacromolecules, 19(10):4059-4067, 2018
Evaluation of dermal adhesive formulations for topical application
Laffleur, F.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 124, 89-94, 2018
Impact of Surfactants on Skin Penetration of Dexpanthenol
Laffleur, F.; Pschick, S.; Barthelmes, J.; Hauptstein, S.; Bernkop-Schnurch, A.
Curr. Drug Deliv., 15(3), 351-356, 2018
Enzyme decorated drug carriers: Targeted swords to cleave and overcome the mucus barrier
Menzel, C.; Bernkop-Schnürch, A.
Adv. Drug Del. Rev., 124, 164-174, 2018
In vivo evaluation of an oral self-emulsifying drug delivery system (SEDDS) for exenatide
Menzel, C.; Holzeisen, T.; Laffleur, F.; Zaichik, S.; Abdulkarim, M.; Gumbleton, M.; Bernkop-Schnürch, A.
J. Control. Rel., 277, 165-172, 2018
Non-ionic thiolated cyclodextrins - the next generation
Moghadam, A.; Ijaz, M.; Asim, M.H.; Mahmood, A.; Jelkmann, M.; Matuszczak, B.; Bernkop-Schnürch, A.
Int. J. Nanomedicine, 13, 4003-4013. eCollection 2018, 2018
Surface phosphorylation of nanoparticles by hexokinase: A powerful tool for cellular uptake improvement
Nazir, I.; Leichner, C.; Le-Vinh, B.; Bernkop-Schnürch, A.
J. Colloid Interface Sci., 516, 384-391, 2018
S-preactivated thiolated glycol chitosan useful to combine mucoadhesion and drug delivery
Perrone, M.; Lopalco, A.; Lopedota, A.; Cutrignelli, A.; Laquintana, V.; Franco, M.; Bernkop-Schnürch, A.; Denora, N.
Eur. J. Pharm. Biopharm., 132, 103-111, 2018
Advanced formulations for intranasal delivery of biologics
Rohrer, J.; Lupo, N.; Bernkop-Schnürch, A.
Int. J. Pharm., 553, 8-20, 2018
Self-emulsifying drug delivery systems changing their zeta potential via a flip-flop mechanism
Salimi, E.; Le-Vinh, B.; Zahir-Jouzdani, F.; Matuszczak, B.; Ghaee, A.; Bernkop-Schnürch, A.
Int. J. Pharm., 550, 200-206, 2018
Trypsin decorated self-emulsifying drug delivery systems (SEDDS): Key to enhanced mucus permeation
Shahzadi, I.; Dizdarević, A.; Efiana, N.A.; Matuszczak, B.; Bernkop-Schnürch, A.
J. Colloid Interface Sci., 531, 253-260, 2018
Glyceryl ester surfactants: Promising excipients to enhance the cell permeating properties of SEDDS
Zahir-Jouzdani, F.; Lupo, N.; Hermann, M.; Prüfert, F.; Atyabi, F.; Bernkop Schnürch, A.
Eur. J. Pharm. Biopharm., 129, 154-161, 2018
In situ gelling and mucoadhesive polymers: why do they need each other?
Zahir-Jouzdani, F.; Wolf, J.D.; Atyabi, F.; Bernkop-Schnürch, A.
Expert Opin. Drug Deliv., 15(10), 1007-1019, 2018
Development of self-emulsifying drug delivery systems (SEDDS) for ciprofloxacin with improved mucus permeating properties
Zaichik, S.; Steinbring, C.; Menzel, C.; Knabl, L.; Orth-Höller, D.; Ellemunter, H.; Niedermayr, K.; Bernkop-Schnürch, A.
Int. J. Pharm., 547, 282-290, 2018
Oral Delivery of Biologics - Back to the Roots
Bernkop-Schnürch, A.
10th International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems (Pharmaceutica 2017), London, UK, 2017
Mucoadhesive Polymers: Basics, Strategies, and Trends
Bernkop-Schnürch, A.
Concise Encyclopedia of Biomedical Polymers and Polymeric Biomaterials, 2017
Nanoparticular delivery system for a secretoneurin derivative induces angiogenesis in a hind limb ischemia model.
Albrecht-Schgoer, K.; Barthelmes, J.; Schgoer, W.; Theurl, M.; Nardin, I.; Lener, D.; Gutmann, C.; Dünnhaupt, S.; Bernkop-Schnürch, A.; Kirchmair, R.
J. Control. Rel., 250, 1-8, 2017
Improved mucoadhesive properties of self-nanoemulsifying drug delivery systems (SNEDDS) by introducing acyl chitosan.
Efiana, N.A.; Mahmood, A.; Lam, H.T.; Zupančič, O.; Leonaviciute, G.; Bernkop-Schnürch, A.
Int. J. Pharm., 519, 206-212, 2017
About the impact of water movement on the permeation behaviour of nanoparticles in mucus.
Fabiano, A.; Zambito, Z.; Bernkop-Schnürch, A.
Int. J. Pharm., 517, 279-285, 2017
Zeta potential changing self-emulsifying drug delivery systems containing phosphorylated polysaccharides.
Griesser, J.; Burtscher, S.; Köllner, S.; Nardin, I.; Prüfert, F.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 119, 264-270, 2017
Hydrophobic ion pairing: Key to highly payloaded self-emulsifying peptide drug delivery systems.
Griesser, J.; Hetényi, G.; Moser, M.; Demarne, F.; Jannin, V.; Bernkop-Schnürch, A.
Int. J. Pharm., 520, 267-274, 2017
Thiolated polymers: evaluation of their potential as dermoadhesive excipients.
Grießinger, J.A.; Bonengel, S.; Partenhauser, A.; Ijaz, M.; Bernkop-Schnürch, A.
Drug Dev. Ind. Pharm., 43(2), 204-212, 2017
Comparison of the protective effect of self-emulsifying peptide drug delivery systems towards intestinal proteases and glutathione.
Hetényi, G.; Griesser, J.; Moser, M.; Demarne, F.; Jannin, V.; Bernkop-Schnürch, A.
Int. J. Pharm., 523, 357-365, 2017
Combination of SEDDS and Preactivated Thiomer Technology: Incorporation of a Preactivated Thiolated Amphiphilic Polymer into Self-Emulsifying Delivery Systems.
Hetényi, G.; Griesser, J.; Nardin, I.; Bernkop-Schnürch, A.
Pharm. Res., 34(6), 1171-1179, 2017
Development of pre-activated α-cyclodextrin as a mucoadhesive excipient for intra-vesical drug delivery.
Ijaz, M.; Prantl, M.; Lupo, N.; Laffleur, F.; Hussain Asim, M.; Matuszczak, B.; Bernkop-Schnürch, A.
Int J Pharm., 534, 339-347, 2017
Self-emulsifying drug delivery systems: Design of a novel vaginal delivery system for curcumin.
Köllner, S.; Nardin, I.; Markt, R.; Griesser, J.; Prüfert, F.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 115, 268-275, 2017
Evaluation of peptide drug delivery via skin barrier-impact of permeation enhancers.
Laffleur, F.; Bernkop-Schnürch, A.
J. Drug Del. Sci.Tech., 41, 191-196, 2017
Comparison of mucoadhesive and cohesive features of poly(acrylic acid)-conjugates respective their molecular mass.
Laffleur, F.; Knapp, K.; Suchaoin, W.; Partenhauser, A.; Netsomboon, K.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 113, 149-156, 2017
Comprehensive mucoadhesive study of anionic polymers and their derivate.
Laffleur, F.; Netsomboon, K.; Bernkop-Schnürch, A.; Westmeier, D.; Stauber, R.H.; Docter, D.
European Polymer Journal, 93, 314-322, 2017
Thiomers: Impact of in situ cross-linkers on mucoadhesive properties.
Lam, H.T.; Leonaviciute, G.; Zupančič, O.; Bernkop-Schnürch, A.
Eur. J. Pharm. Sci., 106, 41-48, 2017
Development and in vitro characterization of a papain loaded mucolytic self-emulsifying drug delivery system (SEDDS).
Leichner, C.; Menzel, C.; Laffleur, F.; Bernkop-Schnürch, A.
Int. J. Pharm., 530, 346-353, 2017
Self-emulsifying drug delivery systems (SEDDS): Proof-of-concept how to make them mucoadhesive.
Leonaviciute, G.; Adamovic, N.T.; Lam, H.T.; Rohrer, J.; Partenhauser, A.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 112, 51-57, 2017
Inhibitory effect of emulsifiers in sedds on protease activity: Just an illusion?
Lupo, N.; Fidahic, U.; Hetényi, G.; Griesser, J.; Bernkop-Schnürch, A.
Int. J. Pharm., 526, 23-30, 2017
Entirely S-protected chitosan: A promising mucoadhesive excipient for metronidazole vaginal tablets.
Lupo, N.; Fodor, B.; Muhammad, I.; Yaqoob, M.; Matuszczak, B.; Bernkop-Schnürch, A.
Acta Biomater., 64, 106-115, 2017
Role of sonication pre-treatment and cation valence in the sol-gel transition of nano-cellulose suspensions.
Maestri, C.A.; Abrami, M.; Hazan, S.; Chistè, E.; Golan, Y.; Rohrer, J.; Bernkop-Schnürch, A.; Grassi, M.; Scarpa, M.; Bettotti, P.
Sci. Rep., 7(1), 11129, 2017
Protease-functionalized mucus penetrating microparticles: In-vivo evidence for their potential.
Mahmood, A.; Laffleur, F.; Leonaviciute, G.; Bernkop-Schnürch, A.
Int. J. Pharm., 532, 177-184, 2017
Thiolated chitosan micelles: Highly mucoadhesive drug carriers.
Mahmood, A.; Lanthaler, M.; Laffleur, F.; Huck, C.W.; Bernkop-Schnürch, A.
Carbohydr. Polym., 167, 250-258, 2017
Nasal drug delivery: Design of a novel mucoadhesive and in situ gelling polymer.
Menzel, C.; Jelkmann, M.; Laffleur, F.; Bernkop-Schnürch, A.
Int. J. Pharm., 517, 196-202, 2017
Multifunctional adhesive polymers: Preactivated thiolated chitosan-EDTA conjugates.
Netsomboon, K.; Suchaoin, W.; Laffleur, F.; Prüfert, F.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 111, 26-32, 2017
Preactivated silicone oil as potential long-term vitreous replacement with nonemulsifying properties.
Partenhauser, A.; Netsomboon, K.; Pereira de Sousa, I.; Laffleur, F.; Bernkop-Schnürch, A.
J. Biomed. Mater. Res. B Appl. Biomater., 105(3), 551-559, 2017
Preactivated thiolated glycogen as mucoadhesive polymer for drug delivery.
Perrone, M.; Lopalco, A.; Lopedota, A.; Cutrignelli, A.; Laquintana, V.; Douglas, J.; Franco, M.; Liberati, E.; Russo, V.; Tongiani, S.; Denora, N.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 119, 161-169, 2017
Natural dendrimers: Synthesis and in vitro characterization of glycogen-cysteamine conjugates.
Perrone, M.; Lopedota, A.; Liberati, E.; Russo, V.; Cutrignelli, A.; Laquintana, V.; de Sousa, I.P.; Franco, M.; Tongiani, S.; Denora, N.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 115, 168-176, 2017
ζ potential changing nanoparticles as cystic fibrosis transmembrane conductance regulator gene delivery system: an in vitro evaluation.
Prüfert, F.; Bonengel, S.; Köllner, S.; Griesser, J.; Wilcox, M.D.; Chater, P.I.; Pearson, J.P.; Bernkop-Schnürch, A.
Nanomedicine (Lond)., 12(22), 2713-2724, 2017
Enhancing the efficiency of thiomers: Utilizing a highly mucoadhesive polymer as backbone for thiolation and preactivation.
Prüfert, F.; Bonengel, S.; Menzel, C.; Bernkop-Schnürch, A.
Eur. J. Pharm. Sci., 96, 309-315, 2017
Thiolated gelatin films: Renaissance of gelatin as sustained intraoral dosage form.
Rohrer, J.; Partenhauser, A.; Zupančič, O.; Leonavičiūtė, G.; Podričnik, S.; Bernkop-Schnürch, A.
European Polymer Journal, 87, 48-59, 2017
Nanocarriers protecting toward an intestinal pre-uptake metabolism.
Suchaoin, W.; Bernkop-Schnürch, A.
Nanomedicine (Lond)., 12(3), 255-269, 2017
Zeta-potential-changing nanoparticles conjugated with cell-penetrating peptides for enhanced transfection efficiency.
Suchaoin, W.; Mahmood, A.; Netsomboon, K.; Bernkop-Schnürch, A.
Nanomedicine (Lond)., 12(9), 963-975, 2017
Lipophilic peptide character - What oral barriers fear the most.
Zupančič, O.; Bernkop-Schnürch, A.
J. Control. Rel., 255, 242-257, 2017
Storage Stability of Bivalirudin: Hydrophilic Versus Lipophilic Solutions.
Zupančič, O.; Grießinger, J.A.; Lam, H.T.; Bernkop-Schnürch, A.
J. Pharm. Sci., 106(5), 1322-1330, 2017
Development and in vitro characterization of self-emulsifying drug delivery system (SEDDS) for oral opioid peptide delivery.
Zupančič, O.; Rohrer, J.; Thanh Lam, H.; Grießinger, J.A.; Bernkop-Schnürch, A.
Drug Dev. Ind. Pharm., 43(10), 1694-1702, 2017
Charge changing phosphorylated polymers: Proof of in situ mucoadhesive properties
Bonengel, S.; Jelkmann, M.; Oh, S.; Mahmood, A.; Ijaz, M.; Bernkop-Schnürch, A.
J. Pharm. Biopharm., 105, 203-208, 2016
Zeta potential changing phosphorylated nanocomplexes for pDNA delivery
Bonengel, S.; Prüfert, F.; Jelkmann, M.; Bernkop-Schnürch, A.
Int. J. Pharm., 504, 117-124, 2016
In vitro characterization of insulin containing thiomeric microparticles as nasal drug delivery system
Deutel, B.; Laffleur, F.; Palmberger, T.; Saxer, A.; Thaler, M.; Bernkop-Schnürch, A.
J. Pharm. Sci., 81, 157-161, 2016
Assembly and in vitro characterization of thiomeric nanoparticles
Deutel, B.; Laffleur, F.; Thaurer, M.; Thaler, M.; Bernkop-Schnürch, A.
Drug Dev. Ind., 42, 730-736, 2016
Evaluation of the impact of multivalent metal ions on the permeation behavior of Dolutegravir sodium
Grießinger, J.A.; Hauptstein, S.; Laffleur, F.; Netsomboon, K.; Bernkop-Schnürch, A.
Drug Dev. Ind. Pharm., 42, 1118-1126, 2016
Thiolated α-Cyclodextrin: The Invisible Choice to Prolong Ocular Drug Residence Time
Ijaz, M.; Ahmad, M.; Akhtar, N.; Laffleur, F.; Bernkop-Schnürch, A.
J. Pharm., 105, 2848-2854, 2016
Development of oral self nano-emulsifying delivery system(s) of lanreotide with improved stability against presystemic thiol-disulfide exchange reactions
Ijaz, M.; Bonengel, S.; Zupančič, O.; Yaqoob, M.; Hartl, M.; Hussain, S.; Huck, C.W.; Bernkop-Schnürch, A.
Expert Opin. Drug Deliv., 13, 923-929, 2016
Thiolated Cyclodextrin: Development of a Mucoadhesive Vaginal Delivery System for Acyclovir
Ijaz, M.; Griessinger, J.A.; Mahmood, A.; Laffleur, F.; Bernkop-Schnürch, A.
Pharm. Sci., 105, 1714-1720, 2016
Mucoadhesive therapeutic compositions: a patent review (2011-2014)
Laffleur, F.
Expert Opin. Ther. Pat., 26(3), 377-388, 2016
Design, characterization and in vitro evaluation of a novel thiolated polymer: preactivated carboxymethyl cellulose
Laffleur, F.; Bacher, L.; Netsomboon, K.
Deliv., 7(1),7-14, 2016
Next generation of buccadhesive excipient: Preactivated carboxymethyl cellulose
Laffleur, F.; Bacher, L.; Vanicek, S.; Menzel, C.; Muhammad, I.
Int. J. Pharm., 500, 120-127, 2016
In vitro evaluation of thio-poly acrylic acid for intraoral delivery
Laffleur, F.; Leder, N.; Barthelmes, J.
Drug Deliv., 23(6), 2065-2073, 2016
Development of mucoadhesive thio-carboxymethyl cellulose for application in buccal delivery of drugs
Laffleur, F.; Messirek, A.
Ther. Deliv., 7(2), 63-71, 2016
Design and evaluation of buccal-adhesive system made of modified xanthan
Laffleur, F.; Michalek, M.; Suchaoin, W.; Ijaz, M.
Ther. Deliv., 7(7):423-429, 2016
Design, modification and in vitro evaluation of pectin's bucco-adhesiveness
Laffleur, F.; Zilio, M.; Menzel, C.; Lupo, N.; Schmutzler, M.
Ther. Deliv., 7(6),369-375, 2016
Modified biomolecule as potential vehicle for buccal delivery of doxepin
Laffleur, F.; Zilio, M.; Shuwisitkul, D.
Ther. Deliv., 7(10):683-689, 2016
S-protected thiolated hydroxyethyl cellulose (HEC): Novel mucoadhesive excipient with improved stability
Leonaviciute, G.; Bonengel, S.; Mahmood, A.; Ahmad Idrees, M.; Bernkop-Schnürch, A.
Polym., 144, 514-521, 2016
Preactivated thiolated pullulan as a versatile excipient for mucosal drug targeting
Leonaviciute, G.; Suchaoin, W.; Matuszczak, B.; Lam, H.T.; Mahmood, A.; Bernkop-Schnürch, A.
Polym., 151, 743-751, 2016
Impact of lipases on the protective effect of SEDDS for incorporated peptide drugs towards intestinal peptidases
Leonaviciute, G.; Zupančič, O.; Prüfert, F.; Rohrer, J.; Bernkop-Schnürch, A.
J. Pharm., 508, 102-108, 2016
Mucoadhesive Polymers: Basics, Strategies, and Trends
Bernkop-Schnürch, A.
Encyclopedia of Biomedical Polymers and Polymeric Biomaterials, 2015
Nanoparticle diffusion within intestinal mucus: Three-dimensional response analysis dissecting the impact of particle surface charge, size and heterogeneity across polyelectrolyte, pegylated and viral particles
Abdulkarim, M.; Agulló, N.; Cattoz, B.; Griffiths, P.; Bernkop-Schnürch, A.; Borros, S.G.; Gumbleton, M.
J. Pharm. Biopharm., 2015
Design and evaluation of an intravesical delivery system for superficial bladder cancer: preparation of gemcitabine HCl-loaded chitosan–thioglycolic acid nanoparticles and comparison of chitosan/poloxamer gels as carriers
Ay Şenyiğit, Z.; Karavana, S.Y.; İlem-Özdemir, D.; Çalışkan, Ç.; Waldner, C.; Şen, S.; Bernkop-Schnürch, A.; Baloğlu, E.
J. Nanomedicine, 2015
Thiolated alkyl-modified carbomers: Novel excipients for mucoadhesive emulsions
Bonengel, S.; Hauptstein, S.; Leonaviciute, G.; Griessinger, J.; Bernkop-Schnürch, A.
J. Pharm. Sci., 2015
Polyethylene imine-6-phosphogluconic acid nanoparticles--a novel zeta potential changing system
Bonengel, S.; Prüfert, F.; Perera, G.; Schauer, J.; Bernkop-Schnürch, A.
J. Pharm., 2015
Thiolated nanocarriers for oral delivery of hydrophilic macromolecular drugs
Dünnhaupt, S.; Barthelmes, J.; Köllner, S.; Sakloetsakun, D.; Shahnaz, G.; Düregger, A.; Bernkop-Schnürch, A.
Polym., 2015
Nano-carrier systems: Strategies to overcome the mucus gel barrier
Dünnhaupt, S.; Kammona, O.; Waldner, C.; Kiparissides, C.; Bernkop-Schnürch, A.
J. Pharm. Biopharm., 2015
Thiomers: Influence of molecular mass and thiol group content of poly(acrylic acid) on efflux pump inhibition
Grabovac, V.; Laffleur, F.; Bernkop-Schnürch, A.
J. Pharm., 2015
Methods to determine the interactions of micro- and nanoparticles with mucus
Grießinger, J.; Dünnhaupt, S.; Cattoz, B.; Griffiths, P.; Oh, S.; Gómez, S.B.; Wilcox, M.; Pearson, J.; Gumbleton, M.; Abdulkarim, M.; Pereira de Sousa, I.; Bernkop-Schnürch, A.
J. Pharm. Biopharm., 2015
Synthesis and in vitro characterization of a novel S-protected thiolated alginate
Hauptstein, S.; Dezorzi, S.; Prüfert, F.; Matuszczak, B.; Bernkop-Schnürch, A.
Polym., 2015
Self-nanoemulsifying drug delivery systems as novel approach for pDNA drug delivery
Hauptstein, S.; Prüfert, F.; Bernkop-Schnürch, A.
J. Pharm., 2015
Non-clinical safety evaluation of intranasal iota-carrageenan
Hebar, A.; Koller, C.; Seifert, J.M.; Chabicovsky, M.; Bodenteich, A.; Bernkop-Schnürch, A.; Grassauer, A.; Prieschl-Grassauer, E.
PLoS One, 2015
Preactivated thiomers: their role in drug delivery
Ijaz, M.; Bernkop-Schnürch, A.
Expert Opin. Drug Deliv., 2015
Synthesis and characterization of thiolated β-cyclodextrin as a novel mucoadhesive excipient for intra-oral drug delivery
Ijaz, M.; Matuszczak, B.; Rahmat, D.; Mahmood, A.; Bonengel, S.; Hussain, S.; Huck, C.W.; Bernkop-Schnürch, A.
Polym., 2015
Mucus permeating thiomer nanoparticles
Köllner, S.; Dünnhaupt, S.; Waldner, C.; Hauptstein, S.; Pereira de Sousa, I.; Bernkop-Schnürch, A.
J. Pharm. Biopharm., 2015
Development of novel mucoadhesive hyaluronic acid derivate as lubricant for the treatment of dry eye syndrome
Laffleur, F.; Dachs, S.
Deliv., 2015
Evaluation of functional characteristics of preactivated thiolated chitosan as potential therapeutic agent for dry mouth syndrome
Laffleur, F.; Fischer, A.; Schmutzler, M.; Hintzen, F.; Bernkop-Schnürch, A.
Acta Biomater., 2015
Permeation enhancement via thiolation: in vitro and ex vivo evaluation of hyaluronic acid-cysteine ethyl ester
Laffleur, F.; Psenner, J.; Suchaoin, W.
Pharm. Sci., 2015
A potential tailor-made hyaluronic acid buccal delivery system comprising rotigotine for Parkinson's disease?
Laffleur, F.; Wagner, J.; Barthelmes, J.
Future Med. Chem., 2015
In vitro and ex vivo evaluation of biomaterials' distinctive properties as a result of thiolation
Laffleur, F.; Wagner, J.; Mahmood, A.
Future Med. Chem., 2015
Self-emulsifying drug delivery systems in oral (poly)peptide drug delivery
Leonaviciute, G.; Bernkop-Schnürch, A.
Expert Opin. Drug Deliv., 2015
Oral self-nanoemulsifying peptide drug delivery systems: impact of lipase on drug release
Mahjub, R.; Dorkoosh, F.A.; Rafiee-Tehrani, M.; Bernkop-Schnürch, A.
Microencap., 2015
An in-vitro exploration of permeation enhancement by novel polysulfonate thiomers
Mahmood, A.; Bonengel, S.; Laffleur, F.; Ijaz, M.; Leonaviciute, G.; Bernkop-Schnürch, A.
J. Pharm., 2015
In vivo evaluation of anionic thiolated polymers as oral delivery systems for efflux pump inhibition
Palmberger, T.F.; Laffleur, F.; Greindl, M.; Bernkop-Schnürch, A.
J. Pharm., 2015
Thiolated silicone oil: synthesis, gelling and mucoadhesive properties
Partenhauser, A.; Laffleur, F.; Rohrer, J.; Bernkop-Schnürch, A.
Acta Biomater., 2015
Nanoparticles decorated with proteolytic enzymes, a promising strategy to overcome the mucus barrier
Pereira de Sousa, I.; Cattoz, B.; Wilcox, M.D.; Griffiths, P.C.; Dalgliesh, R.; Rogers, S.; Bernkop-Schnürch, A.
J. Pharm. Biopharm., 2015
Mucus permeating carriers: formulation and characterization of highly densely charged nanoparticles
Pereira de Sousa, I.; Steiner, C.; Schmutzler, M.; Wilcox, M.D.; Veldhuis, J.; Pearson, J.P.; Huck, C.W.; Salvenmoser, W.; Bernkop-Schnürch, A.
J. Pharm. Biopharm., 2015
Development of phosphorylated nanoparticles as zeta potential inverting systems
Perera, G.; Zipser, M.; Bonengel, S.; Salvenmoser, W.; Bernkop-Schnürch, A.
J. Pharm. Biopharm., 2015
Synthesis and in vitro characterization of preactivated thiolated gelatin
Rohrer, J.; Zupancic, O.; Suchaoin, W.; Netsoomboon, K.; Laffleur, F.; Oh, S.; Bernkop-Schnürch, A.
European Polymer Journal, 2015
Synthesis and In Vitro Evaluation of Thiolated Carrageenan
Suchaoin, W.; Bonengel, S.; Hussain, S.; Huck, C.W.; Ma, B.N.; Bernkop-Schnürch, A.
Pharm. Sci., 2015
Thiomers
Müller, C.; Bernkop-Schnürch, A.
Mucoadhesive Materials and Drug Delivery Systems, 2014
Thiomers - From bench to market
Bonengel, S.; Bernkop-Schnürch, A.
Control. Rel., 2014
Thiolated and S-protected hydrophobically modified cross-linked poly(acrylic acid) - A new generation of multifunctional polymers
Bonengel, S.; Hauptstein, S.; Perera, G.; Bernkop-Schnürch, A.
J. Pharm. Biopharm., 2014
Synthesis and characterization of pH tolerant and mucoadhesive (thiol-polyethylene glycol) chitosan graft polymer for drug delivery
Hauptstein, S.; Bonengel, S.; Griessinger, J.; Bernkop-Schnürch, A.
Pharm. Sci., 2014
Preactivated thiolated poly(methacrylic acid-co-ethyl acrylate): Synthesis and evaluation of mucoadhesive potential
Hauptstein, S.; Bonengel, S.; Rohrer, J.; Bernkop-Schnürch, A.
J. Pharm. Sci., 2014
Development and in vitro evaluation of a buccal drug delivery system based on preactivated thiolated pectin
Hauptstein, S.; Hintzen, F.; Müller, C.; Ohm, M.; Bernkop-Schnürch, A.
Drug Dev. Ind. Pharm., 2014
In vivo evaluation of an oral self-microemulsifying drug delivery system (SMEDDS) for leuprorelin
Hintzen, F.; Perera, G.; Hauptstein, S.; Müller, C.; Laffleur, F.; Bernkop-Schnürch, A.
J. Pharm., 2014
Development and in vitro evaluation of slippery nanoparticles for enhanced diffusion through native mucus
Laffleur, F.; Hintzen, F.; Shahnaz, G.; Rahmat, D.; Leithner, K.; Bernkop-Schnürch, A.
Nanomedicine, 2014
Chemical modification of hyaluronic acid for intraoral application
Laffleur, F.; Röggla, J.; Idrees, M.A.; Griessinger, J.
Pharm. Sci., 2014
Mucoadhesive polymers for buccal drug delivery
Laffleur, F.
Drug Dev Ind Pharm., 2014
In vivo evaluation of thiolated chitosan tablets for oral insulin delivery
Millotti, G.; Laffleur, F.; Perera, G.; Vigl, C.; Pickl, K.; Sinner, F.; Bernkop-Schnürch, A.
Pharm. Sci., 2014
Development of thiolated poly(acrylic acid) microparticles for the nasal administration of exenatide
Millotti, G.; Vetter, A.; Leithner, K.; Sarti, F.; Shahnaz-Bano, G.; Augustijns, P.; Bernkop-Schnürch, A.
Drug Dev. Ind. Pharm., 2014
Development and in vivo evaluation of papain-functionalized nanoparticles
Müller, C.; Perera, G.; König, V.; Bernkop-Schnürch, A.
J. Pharm. Biopharm., 2014
Preactivated hyaluronic acid: A potential mucoadhesive polymer for vaginal delivery
Nowak, J.; Laffleur, F.; Bernkop-Schnürch, A.
J. Pharm., 2014
Pre-systemic metabolism of orally administered drugs and strategies to overcome it
Pereira de Sousa, I.; Bernkop-Schnürch, A.
Control. Rel., 2014
Enzyme-Functionalized PLGA Nanoparticles with Enhanced Mucus Permeation Rate
Samaridou, E.; Karidi, K.; Pereira de Sousa, I.; Cattoz, B.; Griffiths, P.; Kammona, O.; Bernkop-Schnürch, A.; Kiparissides. C.
Nano LIFE, 2014
Development of a dosage form for accelerated release
Waldner, C.; Friedl, H.E.; Dünnhaupt, S.; Köllner, S.; Leonaviciute, G.; Bernkop-Schnürch, A.
J. Pharm., 2014
Thiolated particles as effective intravesical drug delivery systems for treatment of bladder-related diseases
Barthelmes, J.; Dünnhaupt, S.; Unterhofer, S.; Perera, G.; Schlocker, W.; Bernkop-Schnürch, A.
Nanomedicine, 2013
Nanocarrier systems for oral drug delivery: Do we really need them?
Bernkop-Schnürch, A.
European Journal of Pharmaceutical Sciences, 2013
Development and evaluation of a novel mucus diffusion test system approved by self-nanoemulsifying drug delivery systems
Friedl, H.; Dünnhaupt, S.; Hintzen, F.; Waldner, C.; Parikh, S.; Pearson, J.P.; Wilcox, M.D.; Bernkop-Schnürch, A.
Journal of Pharmaceutical Sciences, 2013
Preactivated thiomers for vaginal drug delivery vehicles
Friedl, H.E.; Dünnhaupt, S.; Waldner, C.; Bernkop-Schnürch, A.
Biomaterials, 2013
Liposomes coated with thiolated chitosan enhance oral peptide delivery to rats
Gradauer, K.; Barthelmes, J.; Vonach, C.; Almer, G.; Mangge, H.; Teubl, B.; Roblegg, E.; Dünnhaupt, S.; Fröhlich, E.; Bernkop-Schnürch, A.; Prassl, R.
Journal of Controlled Release, 2013
Thiomer-coated liposomes harbor permeation enhancing and efflux pump inhibitory properties
Gradauer, K.; Dünnhaupt, S.; Vonach, C.; Szöllösi, H.; Pali-Schöll, I.; Mangge, H.; Jensen-Jarolim, E.; Bernkop-Schnürch, A.; Prassl, R.
Journal of Controlled Release, 2013
Preactivated thiomers: Evaluation of gastroretentive minitablets
Hauptstein, S.; Müller, C.; Dünnhaupt, S.; Laffleur, F.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 2013
Synthesis and in vitro characterization of entirely S-protected thiolated pectin for drug delivery
Hintzen, F.; Hauptstein, S.; Perera, G.; Bernkop-Schnürch, A.
European Journal of Pharmaceutics and Biopharmaceutics, 2013
In vitro and ex vivo evaluation of an intestinal permeation enhancing self-microemulsifying drug delivery system (SMEDDS)
Hintzen, F.; Laffleur, F.; Sarti, F.; Müller, C.; Bernkop-Schnürch, A.
Journal of Drug Delivery Science and Technology, 2013
Strategies for improving mucosal drug delivery
Laffleur, F.; Bernkop-Schnürch, A.
Nanomedicine, 2013
Enzymatic degradation of thiolated chitosan
Laffleur, F.; Hintzen, F.; Rahmat, D.; Shahnaz, G.; Millotti, G.; Bernkop-Schnürch, A.
Drug Development and Industrial Pharmacy, 2013
Design and in vitro evaluation of a novel polymeric excipient for buccal applications
Laffleur, F.; Shahnaz, G.; Islambulchilar, Z.; Bernkop-Schnürch, A.
Future Medicinal Chemistry, 2013
Preparation and characterization of mucus-penetrating papain/polyacrilic acid nanoparticles for oral drug delivery applications
Müller, C.; Leithner, K.; Hauptstein, S.; Hintzen, F.; Salvenmoser, W.; Bernkop-Schnürch, A.
Journal of Nanoparticle Research, 2013
Thiopyrazole preactivated chitosan: Combining mucoadhesion and drug delivery
Müller, C.; Ma, B.N.; Gust, R.; Bernkop-Schnürch, A.
Acta Biomaterialia, 2013
Thiolated hydroxyethyl cellulose: Design and in vitro evaluation of mucoadhesive and permeation enhancing nanoparticles
Rahmat, D.; Müller, C.; Barthelmes, J.; Shahnaz, G.; Martien, R.; Bernkop-Schnürch, A.
European Journal of Pharmaceutics and Biopharmaceutics, 2013
HEC-cysteamine particles: influence of particle size, zeta potential, morphology and sulfhydryl groups on permeation enhancing properties
Rahmat, D.; Müller, C.; Shahnaz, G.; Laffleur, F.; Leithner, K.; Khan, M.I.; Martien, R.; Bernkop-Schnürch, A.
Drug Development and Industrial Pharmacy, 2013
Combining two technologies: Multifunctional polymers and self-nanoemulsifying drug delivery system (SNEDDS) for oral insulin administration
Sakloetsakun, D.; Dünnhaupt, S.; Barthelmes, J.; Perera, G.; Bernkop-Schnürch, A.
International Journal of Biological Macromolecules, 2013
Development and in vivo evaluation of an oral vitamin B12 delivery system
Sarti, F.; Müller, C.; Iqbal, J.; Perera, G.; Laffleur, F.; Bernkop-Schnürch, A.
European Journal of Pharmaceutics and Biopharmaceutics, 2013
Efficient MRI labeling of endothelial progenitor cells: Design of thiolated surface stabilized superparamagnetic iron oxide nanoparticles
Shahnaz, G.; Kremser, C.; Reinisch, A.; Vetter. A.; Laffleur, F.; Rahmat, D.; Iqbal, J.; Dünnhaupt, S.; Salvenmoser, W.; Tessadri, R.; Griesser, U.; Bernkop-Schnürch, A.
European Journal of Pharmaceutics and Biopharmaceutics, 2013
Pharmaceutical Non-Viral Formulations for Gene Vaccines
Perera, G.; Bernkop-Schnürch, A.
Gene Vaccines, 2012
Chitosan based drug delivery systems
Bernkop-Schnürch, A.; Dünnhaupt, S.
Eur. J. Pharm. Biopharm., 2012
In vivo evaluation of an oral drug delivery system for peptides based on S-protected thiolated chitosan
Dünnhaupt, S.; Barthelmes, J.; Iqbal, J.; Perera, G.; Thurner, C.C.; Friedl, H.; Bernkop-Schnürch, A.
J. Control. Rel., 2012
S-protected thiolated chitosan for oral delivery of hydrophilic macromolecules - Evaluation of permeation enhancing and efflux pump inhibitory properties
Dünnhaupt, S.; Barthelmes, J.; Rahmat, D.; Leithner, K.; Thurner, C.C.; Friedl, H.; Bernkop-Schnürch, A.
Mol. Pharm., 2012
S-protected thiolated chitosan - synthesis and in vitro characterization
Dünnhaupt, S.; Barthelmes, J.; Thurner, C.C.; Waldner, C.; Sakloetsakun, D.; Bernkop-Schnürch, A.
Carbohydr. Polym., 2012
Phosphorothioate Oligonucleotide Quantification by μ-Liquid Chromatography-Mass Spectrometry
Erb, R.; Leithner, K.; Bernkop-Schnürch, A.; Oberacher, H.
AAPS Journal, 2012
Chemical coupling of thiolated chitosan to preformed liposomes improves mucoadhesive properties
Gradauer, K.; Vonach, C.; Leitinger, G.; Kolb, D.; Fröhlich, E.; Roblegg, E.; Bernkop-Schnürch, A.; Prassl, R.
Int. J. Nanomedicine, 2012
Thiomers and thiomer-based nanoparticles in protein and DNA drug delivery
Hauptstein, S.; Bernkop-Schnürch, A.
Expert Opinion Drug Deliv., 2012
In situ gelling properties of anionic thiomers
Hintzen, F.; Laffleur, F.; Sakloetsakun, D.; Leithner, K.; Bernkop-Schnürch, A.
Drug Dev. Ind. Pharm., 2012
Thiomers - Influence of molar mass on in situ gelling properties
Hintzen, F.; Laffleur, F.; Sarti, F.; Shahnaz, G.; Bernkop-Schnürch, A.
Int. J. Pharm., 2012
Preactivated thiomers as mucoadhesive polymers for drug delivery
Iqbal, J.; Shahnaz, G.; Dünnhaupt, S.; Müller, C.; Hintzen, F.; Bernkop-Schnürch, A.
Biomaterials, 2012
Thiolated chitosan - Development and in vivo evaluation of an oral delivery system for leuprolide
Iqbal, J.; Shahnaz, G.; Perera, G.; Hintzen, F.; Sarti, F.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 2012
Thiomers - promising platform for macromolecular drug delivery
Laffleur, F.; Bernkop-Schnürch, A.
Future Med. Chem., 2012
Immobilization of 2-mercaptoethylamine on oxidized chitosan - a substantially mucoadhesive and permeation enhancing polymer
Müller, C.; Rahmat, D.; Sarti, F.; Leithner, K.; Bernkop-Schnürch, A.
J. Mater. Chem., 2012
Thiolated Chitosans - in vitro comparison of mucoadhesive properties
Müller, C.; Verroken, A.; Iqbal, J.; Bernkop-Schnürch, A.
J. Appl. Polym. Sci., 2012
Synergistic effects of conjugating cell penetrating peptides and thiomers on non-viral transfection efficiency
Rahmat, D.; Khan, M.I.; Shahnaz, G.; Sakloetsakun, D.; Perera, G.; Bernkop-Schnürch, A.
Biomaterials, 2012
HEC-cysteamine conjugates - Influence of degree of thiolation on efflux pump inhibitory and permeation enhancing properties
Rahmat, D.; Sakloetsakun, D.; Shahnaz, G.; Sarti, F.; Laffleur, F.; Bernkop-Schnürch, A.
Int. J. Pharm., 2012
In situ crosslinkable thiolated chitosan as scaffold material for tissue engineering
Sakloetsakun, D.; Dünnhaupt, S.; Barthelmes, J.; Pfaller, W.; Bernkop-Schnürch, A.
Adv. Mat. Res., 2012
Poly(acrylic acid)-cysteine for oral vitamin B12 delivery
Sarti, F.; Iqbal, J.; Müller, C.; Shahnaz, G.; Rahmat, D.; Bernkop-Schnürch, A.
Anal. Biochem., 2012
Development and in vivo characterization of a novel peptide drug delivery system providing extended plasma half life
Shahnaz, G.; Iqbal, J.; Rahmat, D.; Perera, G.; Laffleur, F.; Rossi, D.; Bernkop-Schnürch, A.
J. Control. Rel., 2012
Thiolated chitosan nanoparticles for the nasal administration of leuprolide - Bioavailability and pharmacokinetic characterization
Shahnaz, G.; Vetter, A.; Barthelmes, J.; Rahmat, D.; Laffleur, F.; Iqbal, J.; Perera, G.; Schlocker, W.; Dünnhaupt, S.; Augustijns, P.; Bernkop-Schnürch, A.
Int. J. Pharm., 2012
Synthesis and In Vitro Characterization of a Preactivated Thiomer via Polymerization Reaction
Solhi, L.; Schönbichler, S.A.; Dünnhaupt, S.; Barthelmes, J.; Friedl, H.; Huck, C.W.; Bernkop-Schnürch, A.
Biomacromolecules, 2012
Solubilizing agents in nasal formulations and their effect on ciliary beat frequency
Vetter, A.; Augustijns, P.; Bernkop-Schnürch, A.
Toxicol. in vitro, 2012
Preactivated thiomers - Permeation enhancing properties
Wang, X.; Iqbal, J.; Rahmat, D.; Bernkop-Schnürch, A.
Int. J. Pharm., 2012
Chitosan and Thiolated Chitosan
Sarti, F.; Bernkop-Schnürch, A.
Chitosan for Biomaterials I, 2011
Pharmaceutical Dosage Form Containing Tetrahydrobiopterin
Widmann, R.; Bernkop-Schnürch, A.
US Patent App. 13/058,625, 2011
In vitro evaluation of mucoadhesive vaginal tablets of antifungal drugs prepared with thiolated polymer and development of a new dissolution technique for vaginal formulations
Baloglu, E.; Ay Senyıgıt, Z.; Karavana, S.Y.; Vetter, A.; Metın, D.Y.; Hilmioglu Polat, S.; Guneri, T.; Bernkop-Schnürch, A.
Chem.Pharm.Bull., 2011
Thiomer nanoparticles - Stabilization via covalent cross-linking
Barthelmes, J.; Dünnhaupt, S.; Hombach, J.; Bernkop-Schnürch, A.
Drug Deliv., 2011
Development of a mucoadhesive nanoparticulate drug delivery system for a targeted drug release in the bladder
Barthelmes, J.; Perera, G.; Hombach, J.; Dünnhaupt, S.; Bernkop-Schnürch, A.
Int. J. Pharm., 2011
Identification of HN-1-Peptide Target in Head and Neck Squamous Cell Carcinoma Cells
Dudas, J.; Idler, C.; Sprinzl,G.; Bernkop-Schnuerch, A.; Riechelmann, H.
ISRN Oncology, 2011
Distribution of thiolated mucoadhesive nanoparticles on intestinal mucosa
Dünnhaupt, S.; Barthelmes, J.; Hombach, J.; Sakloetsakun, D.; Arkhipova, V.; Bernkop-Schnürch, A.
Int. J. Pharm., 2011
Synthesis and in vitro characterization of a novel PAA-ATP conjugate
Hoyer, H.; Hombach, J.; Perera, G.; Thaurer, M.; Bernkop-Schnürch, A.
Drug Dev. Ind. Pharm., 2011
Thiomers - Inhibition of cytochrome P450 activity
Iqbal, J.; Sakloetsakun, D.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 2011
Development and in vivo evaluation of an oral drug delivery system for paclitaxel
Iqbal, J.; Sarti, F.; Perera, G.; Bernkop-Schnürch, A.
Biomaterials, 2011
Development and in vivo evaluation of a new oral nanoparticulate dosage form for leuprolide based on polyacrylic acid
Iqbal, J.; Vigl, C.; Moser, G.; Gasteiger, M.; Perera, G.; Bernkop-Schnürch, A.
Drug Deliv., 2011
Permeation studies on freshly excised rat gastric mucosa - influence of pH
Leithner, K.; Grabovac, V.; Albrecht, K.; Hombach, J.; Klima, G.; Bernkop-Schnürch, A.
Drug Dev. Ind. Pharm., 2011
Bioadhesive properties of poly(anhydride) nanoparticles coated with different molecular weights chitosan
Llabot, J.M.; Salman, H.; Millotti, G.; Bernkop-Schnürch, A.; Allemandi, D.; Manuel Irache, J.
J. Microencap., 2011
An oral oligonucleotide delivery system based on a thiolated polymer - Development and in vitro evaluation
Martien, R.; Hoyer, H.; Perera, G.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 2011
The use of chitosan-6-mercaptonicotinic acid nanoparticles for oral peptide drug delivery
Millotti, G.; Perera, G.; Vigl, C.; Pickl, K.; Sinner, F.M.; Bernkop-Schnürch, A.
Drug Deliv., 2011
Safety assessment of thiolated polymers - effect on ciliary beat frequency in human nasal epithelial cells
Palmberger, T.; Augustijns, P.; Vetter, A.; Bernkop-Schnürch, A.
Drug Dev. Ind. Pharm., 2011
Thiolated polycarbophil/glutathione - Defining its potential as a permeation enhancer for oral drug administration in comparison to sodium caprate
Perera, G.; Barthelmes, J.; Vetter, A.; Krieg, C.; Uhlschmied, C.; Bonn, G.K.; Bernkop-Schnürch, A.
Drug Deliv., 2011
Design and synthesis of a novel cationic thiolated polymer
Rahmat, D.; Sakloetsakun, D.; Shahnaz, G.; Perera, G.; Kaindl, R.; Bernkop-Schnürch, A.
Int. J. Pharm., 2011
Thiolated chitosans - influence of various sulfhydryl ligands on permeation-enhancing and P-gp inhibitory properties
Sakloetsakun, D.; Iqbal, J.; Millotti, G.; Vetter, A.; Bernkop-Schnürch, A.
Drug Dev. Ind. Pharm., 2011
Intestinal enzymatic metabolism of drugs
Sarti, F.; Barthelmes, J.; Iqbal, J.; Hintzen, F.; Bernkop-Schnürch, A.
J. Pharm. Pharmacol., 2011
Chitosan and Thiolated Chitosan
Sarti, F.; Bernkop-Schnürch, A.
Adv. Polym. Sci., 2011
In vivo evidence of oral vaccination with PLGA nanoparticles containing the immunostimulant monophosphoryl lipid A
Sarti, F.; Perera, G.; Hintzen, F.; Kottib,K.; Karageorgioub, V.; Kammonab, O.; Kiparissides, C.; Bernkop-Schnürch, A.
Biomaterials, 2011
A comprehensive in vitro and in vivo evaluation of thiolated matrix tablets as a gastroretentive delivery system
Senyigit, Z.A.; Vetter, A.; Guneri, T.; Bernkop-Schnürch, A.
Drug Deliv., 2011
Uptake of phenothiazines by the harvested chylomicrons ex vivo model - Influence of self-nanoemulsifying formulation design
Shahnaz, G.; Hartl, M.; Barthelmes, J.; Leithner, K.; Sarti, F.; Hintzen, F.; Rahmat, D.; Salvenmoser, W.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 2011
Thiolated polyacrylic acid-modified iron oxide nanoparticles for in vitro labeling and MRI of stem cells
Vetter, A.; Reinisch, A.; Strunk, D.; Kremser, C.; Hahn, H.W.; Huck, C.W.; Ostermann, T.; Leithner, K.; Bernkop-Schnürch, A.
J. Drug Targ., 2011
Mucoadhesive Drug Delivery Systems
Hombach, J.; Bernkop-Schnürch, A.
Drug Delivery, 2010
In vivo investigation of thiomer-polyvinylpyrrolidon nanoparticles using magnetic resonance imaging
Albrecht, K.; Greindl, M.; Deutel, B.; Kremser, C.; Wolf, C.; Talasz, H.; Stollenwerk, M.; Debbage, P.; Bernkop-Schnürch, A.
J. Pharm. Sci., 2010
Noninvasive delivery systems for peptides and proteins in osteoporosis therapy - a retroperspective
Hoyer, H.; Perera, G.; Bernkop-Schnürch, A.
Drug Dev. Ind. Pharm., 2010
Preparation and evaluation of thiomer nanoparticles via high pressure homogenization
Hoyer, H.; Schlocker, W.; Greindl, M.; Ostermann, T.; Bernkop-Schnürch, A.
J. Microencap., 2010
Design and in vitro evaluation of a novel polymeric P-glycoprotein (P-gp) inhibitor
Iqbal, J.; Hombach, J.; Matuszczak, B.; Bernkop-Schnürch, A.
J. Control. Rel., 2010
6-mercaptonicotinamide-functionalized chitosan - A potential excipient for mucoadhesive drug delivery systems
Millotti, G.; Hoyer, H.; Engbersen, J.F.J.; Bernkop-Schnürch, A.
J. Drug Del. Sci.Tech., 2010
Novel pectin-4-aminothiophenole conjugate microparticles for colon-specific drug delivery
Perera, G.; Barthelmes, J.; Bernkop-Schnürch, A.
J. Control. Rel., 2010
Hydrophobic thiolation of pectin with 4-aminothiophenol - Synthesis and in vitro characterization
Perera, G.; Hombach, J.; Bernkop-Schnürch, A.
AAPS PharmSciTech., 2010
Thiolated Chitosans
Sakloetsakun, D.; Bernkop-Schnürch, A.
J. Drug Del. Sci.Tech., 2010
The impact of vehicles on the mucoadhesive properties of orally administered nanoparticles - a case study
Sakloetsakun, D.; Perera, G.; Hombach, J.; Millotti, G.; Bernkop-Schnürch, A.
AAPS PharmSciTech., 2010
Thiolated hydroxyethylcellulose - synthesis and in vitro evaluation
Sarti, F.; Staaf, A.; Sakloetsakun, D.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 2010
Gastroretentive particles formulated with thiomers - development and in vitro evaluation
Senyigit, Z.A.; Vetter, A.; Guneri, T.; Bernkop-Schnürch, A.
J. Drug Targ., 2010
Synthesis, Characterization, Mucoadhesion and Biocompatibility of Thiolated Carboxymethyldextran-Cysteine Conjugate
Shahnaz, G.; Perera, G.; Sakloetsakun, D.; Rahmat, D.; Bernkop-Schnürch, A.
J. Control. Rel., 2010
Nasal delivery of antisense oligonucleotides - in vitro evaluation of a thiomer/glutathione microparticulate delivery system
Vetter, A.; Bernkop-Schnürch, A.
J. Drug Targ., 2010
Thiolated polycarbophil as an adjuvant for permeation enhancement in nasal delivery of antisense oligonucleotides
Vetter, A.; Martien, R.; Bernkop-Schnürch, A.
J. Pharm. Sci., 2010
Development and in vivo bioavailability study of an oral fondaparinux delivery system
Vetter, A.; Perera, G.; Leithner, K.; Klima, G.; Bernkop-Schnürch, A.
Eur. J. Pharm. Sci., 2010
Low Molecular Mass Permeation Enhancers in Oral Delivery of Macromolecular Drugs
Bernkop-Schnürch, A.
Oral Delivery of Macromolecular Drugs, 2009
Nano- and Microparticles in Oral Delivery of Macromolecular Drugs
Millotti, G.; Bernkop-Schnürch, A.
Oral Delivery of Macromolecular Drugs, 2009
Strategies to prolong the intravaginal residence time of drug delivery systems
Baloglu, E.; Senyigit, Z.A.; Karavana, S.Y.; Bernkop-Schnürch, A.
J.Pharm.Pharmaceut.Sci., 2009
Low molecular mass permeation enhancers in oral delivery of molecular drugs
Bernkop-Schnürch, A.
Oral Delivery of Macromolecular Drugs - Barriers, Strategies and Future Trends, 2009
Absorption and metabolism of resveratrol carboxyesters and methanesulfonate by explanted rat intestinal segments
Biasutto, L.; Marotta, E.; Mattarei, A.; Beltramello, S.; Caliceti, P.; Salmaso, S.; Bernkop-Schnürch, A.; Garbisa, S.; Zoratti, M.; Paradisi, C.
Cellular Physiology and Biochemistry, 2009
In vitro evaluation of natural and methylated cyclodextrins as buccal permeation enhancing systems for omeprazole delivery
Figueiras, A.; Hombach, J.; Veiga, F.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 2009
In vivo evaluation of thiolated poly(acrylic acid) as a drug absorption modulator for MRP2 efflux pump substrates
Greindl, M.; Föger, F.; Hombach, J.; Bernkop-Schnürch, A.
Eur. J. Pharm. Biopharm., 2009
Chitosan solutions and particles - Evaluation of their permeation enhancing potential on MDCK cells used as blood brain barrier model
Hombach, J.; Bernkop-Schnürch, A.
Int. J. Pharm., 2009
Development and in vitro evaluation of a mucoadhesive vaginal delivery system for nystatin
Hombach, J.; Palmberger, T.; Bernkop-Schnürch, A.
J. Pharm. Sci., 2009
Design and in vivo evaluation of a patch system based on thiolated polymers
Hoyer, H.; Greindl, M.; Bernkop-Schnürch, A.
J. Pharm. Sci., 2009
Chitosan-graft-6-mercaptonicotinic acid - synthesis, characterization, and biocompatibility
Millotti, G.; Samberger, C.; Fröhlich, E.; Bernkop-Schnürch, A.
Biomacromolecules, 2009
Insulin-loaded poly(acrylic acid)-cysteine nanoparticles - stability studies towards digestive enzymes of the intestine
Perera, G.; Greindl, M.; Palmberger, T.; Bernkop-Schnürch, A.
Drug Deliv., 2009
In situ gelling properties of chitosan-thioglycolic acid conjugate in the presence of oxidizing agents
Sakloetsakun, D.; Hombach, J.; Bernkop-Schnürch, A.
Biomaterials, 2009
Development of nanoparticulate drug delivery systems based on thiolated poly(acrylic acid)
Thaurer, M.H.; Deutel, B.; Schlocker, W.; Bernkop-Schnürch, A.
J. Microencap., 2009
The efflux pump inhibitory properties of (thiolated) polyallylamines
Vigl, C.; Leithner, K.; Albrecht, K.; Bernkop-Schnürch, A.
J. Drug Del. Sci.Tech., 2009
Modified Chitosans for oral drug delivery
Werle, M.; Takeuchi, H.; Bernkop-Schnürch, A.
J. Pharm. Sci., 2009
Thiolated chitosans in non-invasive drug delivery
Bernkop-Schnürch, A.
Natural-Based Polymers for Biomedical Applications, 2008
Novel insulin thiomer nanoparticles - in vivo evaluation of an oral drug delivery system
Deutel, B.; Greindl, M.; Thaurer, M.; Bernkop-Schnürch, A.
Biomacromolecules, 2008
Correlation of in vitro and in vivo models for the oral absorption of peptide drugs
Föger, F.; Kopf, A.; Loretz, B.; Albrecht, K.; Bernkop-Schnürch, A.
Amino Acids, 2008
Effect of a thiolated polymer on oral paclitaxel absorption and tumor growth in rats
Föger, F.; Malaivijitnond, S.; Wannaprasert, T.; Huck, C.; Bernkop-Schnürch, A.; Werle, M.
Journal of Drug Targeting, 2008
Design and in vivo evaluation of a patch delivery system for insulin based on thiolated polymers
Grabovac, V.; Föger, F.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 2008
Thiolated chitosans - Development and in vitro evaluation of an oral tobramycin sulphate delivery system
Hombach, J.; Hoyer, H.; Bernkop-Schnürch, A.
European Journal of Pharmaceutical Sciences, 2008
Preparation and evaluation of microparticles from thiolated polymers via air jet milling
Hoyer, H.; Schlocker, W.; Kafedjiiski, K.; Bernkop-Schnürch, A.
European Journal of Pharmaceutics and Biopharmaceutics, 2008
In vivo determination of time and location at which mucoadhesive drug delivery systems disintegrate in the gastrointestinal tract
Kremser, C.; Albrecht, K.; Greindl, M.; Wolf, C.; Debbage, P.; Bernkop-Schnürch, A.
Magnetic Resonance Imaging, 2008
Thiolated chitosan nanoparticles - transfection study in the Caco-2 differentiated cell culture
Martien, R.; Loretz, B.; Sandbichler, A.; Bernkop-Schnürch, A.
Nanotechnology, 2008
Thiolated chitosan - Development and in vitro evaluation of an oral delivery system for acyclovir
Palmberger, T.; Hombach, J.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 2008
Near infrared spectroscopy compared to liquid chromatography coupled to mass spectrometry and capillary electrophoresis as a detection tool for peptide reaction monitoring
Petter, C.; Heigl, N.; Bachmann, S.; Huck-Pezzei, V.; Najam-ol-Haq, M.; Bakry, R.; Bernkop-Schnürch, A.; Bonn, G.; Huck, C.
Amino Acids, 2008
Synthesis and characterization of a chitosan-N-acetyl cystein conjugate
Schmitz, T.; Grabovac, V.; Palmberger, T.; Hoffer, M.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 2008
Chitosan-N-acetyl cysteine conjugates - In vitro evaluation of permeation enhancing and P-glycoprotein inhibiting properties
Schmitz, T.; Hombach, J.; Bernkop-Schnürch, A.
Drug Delivery, 2008
Role of P-glycoproteins (P-gp) in the transepithelial transport of indoline alkaloids from Vinca herbaceae
Tsiklauri, L.; Hoyer, H.; Chkhikvadze, G.; Vachnadze, V.; Tsagareishvili, G.; Bakuridze, A.; Bernkop-Schnürch, A.
Khimiko-Farmatsevticheskii Zhurnal (Pharmaceutical Chemistry Journal), 2008
Thiolated chitosans - useful excipients for oral drug delivery
Werle, M.; Bernkop-Schnürch, A.
Journal of Pharmacy and Pharmacology, 2008
Characterisation of the barrier caused by luminally secreted gastro-intestinal proteolytic enzymes for two novel cystine-knot microproteins
Werle, M.; Kolmar, H.; Albrecht, R.; Bernkop-Schnürch, A.
Amino Acids, 2008
Simplifizierte Pepstatin A-Analoga, deren Herstellung und Verwendung
Kratzel, M.; Bernkop-Schnürch, A.; Hiessböck, R.
AT Patent AT 407043, 2007
Thiomers - forms, functions and applications to nanomedicine
Albrecht, K.; Bernkop-Schnürch, A.
Nanomedicine, 2007
Presystemic metabolism of orally administered peptide drugs and strategies to overcome it
Bernkop-Schnürch, A.; Schmitz, T.
Current Drug Metabolism, 2007
Enhanced transport of P-glycoprotein substrate saquinavir in presence of thiolated chitosan
Föger, F.; Kafedjiiski, K.; Hoyer, H.; Loretz, B.; Bernkop-Schnürch, A.
Journal of Drug Targeting, 2007
Development and in vitro evaluation of surface modified poly(lactide-co-glycolide) nanoparticles with chitosan-4-thiobutylamidine
Grabovac, V.; Bernkop-Schnürch, A.
Drug Development and Industrial Pharmacy, 2007
Papain - An effective permeation enhancer for orally administered low molecular weight heparin
Grabovac, V.; Schmitz, T.; Föger, F.; Bernkop-Schnürch, A.
Pharmaceutical Research, 2007
Transport characteristics of a beta sheet breaker peptide across excised bovine nasal mucosa
Greimel, A.; Del Curto, M.; D’Antonio, M.; Bernkop-Schnürch, A.
Drug Development and Industrial Pharmacy, 2007
Oral peptide delivery - in vitro evaluation of thiolated alginate / poly(acrylic acid) microparticles
Greimel, A.; Werle, M.; Bernkop-Schnürch, A.
Journal of Pharmacy and Pharmacology, 2007
Design and evaluation of a new gastrointestinal mucoadhesive patch system containing chitosan-glutathione
Hoyer, H.; Föger, F.; Kafedjiiski, K.; Loretz, B.; Bernkop-Schnürch, A.
Drug Development and Industrial Pharmacy, 2007
Evaluation of in vitro enzymatic degradation of various thiomers and cross-linked thiomers
Kafedjiiski, K.; Föger, F.; Hoyer, H.; Werle, M.; Bernkop-Schnürch, A.
Drug Development and Industrial Pharmacy, 2007
Synthesis and in vitro evaluation of thiolated hyaluronic acid for mucoadhesive drug delivery
Kafedjiiski, K.; Jetti, R.; Föger, F.; Hoyer, H.; Werle, M.; Hoffer, M.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 2007
In vitro cytotoxity testing of non-thiolated and thiolated chitosan nanoparticles for oral gene delivery
Loretz, B.; Bernkop-Schnürch, A.
Nanotoxicology, 2007
Role of sulfhydryl groups in transfection? A case study with chitosan-NAC nanoparticles
Loretz, B.; Thaler, M.; Bernkop-Schnürch, A.
Bioconjugate Chemistry, 2007
Chitosan-thioglycolic acid conjugate - An alternative carrier for oral non-viral gene delivery?
Martien, R.; Loretz, B.; Thaler, M.; Majzoob, S.; Bernkop-Schnürch, A.
Journal of Biomedical Materials Research Part A, 2007
Thiolated polymers - Evaluation of the influence of the amount of covalently attached l-cysteine to poly(acrylic acid)
Palmberger, T.; Albrecht, K.; Loretz, B.; Bernkop-Schnürch, A.
European Journal of Pharmaceutics and Biopharmaceutics, 2007
Development and in vitro evaluation of a thiomer-based nanoparticulate gene delivery system
Schmitz, T.; Bravo-Osuna, I.; Vauthier, C.; Ponchel, G.; Loretz, B.; Bernkop-Schnürch, A.
Biomaterials, 2007
Inhibition of enzymes and secretory transport
Werle, M.; Bernkop-Schnürch, A.
Enhancement in Drug Delivery (Book chapter, CRC Press), 2007
Evaluation and improvement of the properties of the novel cystine-knot microprotein McoEeTI for oral administration
Werle, M.; Kafedjiiski, K.; Kolmar, H.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 2007
Relation between scaffold size and membrane bound enzyme caused degradation of two novel cystine knot microproteins
Werle, M.; Kolmar, H.; Bernkop-Schnürch, A.
Letters in Drug Design & Discovery, 2007
Design and evaluation of a chitosan-aprotinin conjugate for the peroral delivery of therapeutic peptides and proteins susceptible to enzymatic degradation
Werle, M.; Loretz, B.; Entstrasser, D.; Föger, F.
Journal of Drug Targeting, 2007
Comparative in vivo mucoadhesion studies of thiomer formulations using magnetic resonance imaging and fluorescence detection
Albrecht, K.; Greindl, M.; Kremser, C.; Wolf, C.; Debbage, P.; Bernkop-Schnürch, A.
Journal of Controlled Release, 2006
Preparation of thiomer microparticles and in vitro evaluation of parameters influencing their mucoadhesive properties
Albrecht, K.; Zirm, E.; Palmberger, T.; Schlocker, W.; Bernkop-Schnürch, A.
Drug Development and Industrial Pharmacy, 2006
Oral delivery of therapeutic peptides - Barriers and strategies to overcome them
Bernkop-Schnürch, A.
Journal of Drug Targeting, 2006
Polymeric efflux pump inhibitors in oral drug delivery
Bernkop-Schnürch, A.; Grabovac, V.
American Journal of Drug Delivery, 2006
Development of a novel method for the preparation of submicron particles based on thiolated chitosan
Bernkop-Schnürch, A.; Heinrich, A.; Greimel, A.
European Journal of Pharmaceutics and Biopharmaceutics, 2006
In vitro evaluation of the potential of thiomers for the nasal administration of Leu-enkephalin
Bernkop-Schnürch, A.; Obermair, K.; Greimel, A.; Palmberger, T.
Amino Acids, 2006
Thiomers - Preparation and in vitro evaluation of a mucoadhesive nanoparticulate drug delivery system
Bernkop-Schnürch, A.; Weithaler, A.; Albrecht, K.; Greimel, A.
International Journal of Pharmaceutics, 2006
Elaboration and characterization of thiolated chitosan-coated acrylic nanoparticles
Bravo-Osuna, I.; Schmitz, T.; Bernkop-Schnürch, A.; Vauthier, C.; Ponchel, G.
International Journal of Pharmaceutics, 2006
In vivo comparison of various polymeric and low molecular mass inhibitors of intestinal P-glycoprotein
Föger, F.; Hoyer, H.; Kafedjiiski, K.; Thaurer, M.; Bernkop-Schnürch, A.
Biomaterials, 2006
Inhibition of malarial topoisomerase II in Plasmodium falciparum by antisense nanoparticles
Föger, F.; Noonpakdee, W.; Loretz, B.; Joojuntr, S.; Salvenmoser, W.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 2006
In vivo evaluation of an oral delivery system for P-gp substrates based on thiolated chitosan
Föger, F.; Schmitz, T.; Bernkop-Schnürch, A.
Biomaterials, 2006
Improvement of the intestinal membrane permeability of low molecular weight heparin by complexation with stem bromelain
Grabovac, V.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 2006
In vitro evaluation of thiomer microparticles for nasal drug delivery
Greimel, A.; Del Curto, M.; D’Antonio, M.; Palmberger, T.; Sprinzl, G.; Bernkop-Schnürch, A.
Journal of Drug Delivery Science and Technology, 2006
Development of a novel method for the preparation of thiolated polyacrylic acid nanoparticles
Greindl, M.; Bernkop-Schnürch, A.
Pharmaceutical Research, 2006
Oral peptide delivery - Are there remarkable effects on drugs through sulfhydryl conjugation?
Huck, C.; Pezzei, V.; Schmitz, T.; Bonn, G.; Bernkop-Schnürch, A.
Journal of Drug Targeting, 2006
Improved synthesis and in vitro characterization of chitosan-thioethylamidine conjugate
Kafedjiiski, K.; Hoffer, M.; Werle, M.; Bernkop-Schnürch, A.
Biomaterials, 2006
Thiolated chitosan microparticles - A vehicle for nasal peptide drug delivery
Krauland, A.; Guggi, D.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 2006
In vivo evaluation of a nasal insulin delivery system based on thiolated chitosan
Krauland, A.; Leitner, V.; Grabovac, V.; Bernkop-Schnürch, A.
Journal of Pharmaceutical Sciences, 2006
Thiolated chitosans - Design and in vivo evaluation of a mucoadhesive buccal peptide drug delivery system
Langoth, N.; Kahlbacher, H.; Schöffmann, G.; Schmerold, I.; Schuh, M.; Franz, S.; Kurka, P.; Bernkop-Schnürch, A.
Pharmaceutical Research, 2006
In vitro evaluation of chitosan-EDTA conjugate polyplexes as nanoparticulate gene delivery system
Loretz, B.; Bernkop-Schnürch, A.
AAPS Journal, 2006
Oral gene delivery - Strategies to improve stability of pDNA towards intestinal digestion
Loretz, B.; Föger, F.; Werle, M.; Bernkop-Schnürch, A.
Journal of Drug Targeting, 2006
Pectin-cysteine conjugate - synthesis and in-vitro evaluation of its potential for drug delivery
Majzoob, S.; Atyabi, F.; Dorkoosh, F.; Kafedjiiski, K.; Loretz, B.; Bernkop-Schnürch, A.
Journal of Pharmacy and Pharmacology, 2006
Oral gene delivery - Design of polymeric carrier systems shielding towards intestinal enzymatic attack
Martien, R.; Loretz, B.; Bernkop-Schnürch, A.
Biopolymers, 2006
Evaluation of the potential of air jet milling for peptide-loaded microparticle preparation
Schlocker, W.; Gschließer, S.; Bernkop-Schnürch, A.
European Journal of Pharmaceutics and Biopharmaceutics, 2006
Characterisation of the thiol-disulphide chemistry of desmopressin by LC, µ-LC, LC-ESI-MS and Maldi-Tof
Schmitz, T.; Huck, C.; Bernkop-Schnürch, A.
Amino Acids, 2006
Strategies to improve plasma half life time of peptide and protein drugs
Werle, M.; Bernkop-Schnürch, A.
Amino Acids, 2006
Degradation of teriparatide by gastro-intestinal proteolytic enzymes
Werle, M.; Samhaber, A.; Bernkop-Schnürch, A.
Journal of Drug Targeting, 2006
The potential of cystine-knot microproteins as novel pharmacophoric scaffolds in oral peptide drug delivery
Werle, M.; Schmitz, T.; Huang, H.; Wentzel, A.; Kolmar, H.; Bernkop-Schnürch, A.
Journal of Drug Targeting, 2006
Thiomers: A new generation of mucoadhesive polymers
Bernkop-Schnürch, A.
Advanced Drug Delivery Reviews, 2005
Mucoadhesive polymers: strategies, achievements and future challenges
Bernkop-Schnürch, A.
Advanced Drug Delivery Reviews, 2005
Mucoadhesive systems in oral drug delivery
Bernkop-Schnürch, A.
Drug Discovery Today: Technologies, 2005
Thiomers: The next generation of mucoadhesive polymers
Bernkop-Schnürch, A.; Greimel, A.
American Journal of Drug Delivery, 2005
The use of thiolated polymers as carrier matrix in oral peptide delivery - Proof of concept
Bernkop-Schnürch, A.; Pinter, Y.; Guggi, D.; Kahlbacher, H.; Schöffmann, G.; Schuh, M.; Schmerold, I.; Del Curto, M. D.; D’Antonio, M.; Esposito, P.; Huck, C.
Journal of Controlled Release, 2005
Comparison of the mucoadhesive properties of various polymers
Grabovac, V.; Guggi, D.; Bernkop-Schnürch, A.
Advanced Drug Delivery Reviews, 2005
Improved paracellular uptake by the combination of different types of permeation enhancers
Guggi, D.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 2005
Controlled drug delivery systems based on thiolated chitosan microspheres
Imam, M. E.; Bernkop-Schnürch, A.
Drug Development and Industrial Pharmacy, 2005
Synthesis and in vitro evaluation of a novel chitosan–glutathione conjugate
Kafedjiiski, K.; Föger, F.; Werle, M.; Bernkop-Schnürch, A.
Pharmaceutical Research, 2005
Synthesis and in vitro evaluation of a novel thiolated chitosan
Kafedjiiski, K.; Krauland, A. H.; Hoffer, M. H.; Bernkop-Schnürch, A.
Biomaterials, 2005
Synthesis and in vitro characterization of a novel poly(acrylic acid)–glutathione conjugate
Kafedjiiski, K.; Werle, M.; Föger, F.; Bernkop-Schnürch, A.
Journal of Drug Delivery Science and Technology, 2005
Viscoelastic properties of a new in situ gelling thiolated chitosan conjugate
Krauland, A.; Hoffer, M. H.; Bernkop-Schnürch, A.
Drug Development and Industrial Pharmacy, 2005
The use of multifunctional polymers as auxiliary agents in non-invasive peptide delivery
Langoth, N.; Bernkop-Schnürch, A.
Expert Opinion on Therapeutic Patents, 2005
The inhibitory effect of glutathione towards buccal enzymatic degradation of therapeutic peptides (leu-enkephalin, luteinizing hormone-releasing hormone and pituitary adenylate cyclase activating peptide)
Langoth, N.; Bernkop-Schnürch, A.; Kurka, P.
Journal of Drug Delivery Science and Technology, 2005
In vitro evaluation of various buccal permeation enhancing systems for PACAP (pituitary adenylate cyclase-activating polypeptide)
Langoth, N.; Bernkop-Schnürch, A.; Kurka, P.
Pharmaceutical Research, 2005
Development of a mucoadhesive and permeation enhancing buccal delivery system for PACAP (pituitary adenylate cyclase-activating polypeptide)
Langoth, N.; Kalbe, J.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 2005
Preparation and in vitro evaluation of thiolated chitosan microparticles
Maculotti, K.; Genta, I.; Perugini, P.; Imam, M.; Bernkop-Schnürch, A.; Pavanetto, F.
Journal of Microencapsulation, 2005
Oral heparin delivery: Design and in vivo evaluation of a stomach-targeted mucoadhesive delivery system
Schmitz, T.; Leitner, V. M.; Bernkop-Schnürch, A.
Journal of Pharmaceutical Sciences, 2005
In vitro evaluation of the enzymatic stability and permeation behaviour of microbodies: novel carriers for oral peptide drug delivery?
Werle, M.; Schmitz, T.; Wentzel, A.; Kolmar, H.; Bernkop-Schnürch, A.
Pharmacia, 2005
The use of auxiliary agents to improve the mucosal uptake of peptides
Bernkop-Schnürch, A.; Clausen, A.; Guggi, D.
Mini-Reviews in Medicinal Chemistry, 2004
Thiolated chitosans: development and in vivo evaluation of a mucoadhesive permeation enhancing oral drug delivery system
Bernkop-Schnürch, A.; Guggi, D.; Pinter, Y.
Journal of Controlled Release, 2004
Thiomers for oral delivery of hydrophilic macromolecular drugs
Bernkop-Schnürch, A.; Hoffer, M.; Kafedjiiski, K.
Expert Opinion on Drug Delivery, 2004
Thiolated chitosans
Bernkop-Schnürch, A.; Hornof, M.; Guggi, D.
European Journal of Pharmaceutics and Biopharmaceutics, 2004
Preparation and characterisation of thiolated poly(methacrylic acid)–starch compositions
Bernkop-Schnürch, A.; König, V.; Leitner, V.; Krauland, A.; Brodnik, I.
European Journal of Pharmaceutics and Biopharmaceutics, 2004
Thiomers: potential excipients for non-invasive peptide delivery systems
Bernkop-Schnürch, A.; Krauland, A.; Leitner, V.; Palmberger, T.
European Journal of Pharmaceutics and Biopharmaceutics, 2004
Synthesis and in vitro characterisation of a poly(acrylic acid)–homocysteine conjugate
Bernkop-Schnürch, A.; Leitner, V.; Moser, V.
Drug Development and Industrial Pharmacy, 2004
Development of a sustained release dosage form for alpha-lipoic acid. II. Evaluation in human volunteers
Bernkop-Schnürch, A.; Reich-Rohrwig, E.; Marschütz, M.; Schuhbauer, H.; Kratzel, M.
Drug Development and Industrial Pharmacy, 2004
Development of a sustained release dosage form for alpha-lipoic acid. I. Design and in vitro evaluation
Bernkop-Schnürch, A.; Schuhbauer, H.; Clausen, A.; Hanel, R.
Drug Development and Industrial Pharmacy, 2004
Development and in vivo evaluation of an oral insulin–PEG delivery system
Caliceti, P.; Salmaso, S.; Walker, G.; Bernkop-Schnürch, A.
European Journal of Pharmaceutical Sciences, 2004
Comparative evaluation of cytotoxicity of a glucosamine–TBA conjugate and a chitosan–TBA conjugate
Guggi, D.; Langoth, N.; Hoffer, M.; Wirth, M.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 2004
Matrix tablets based on thiolated poly(acrylic acid): pH-dependent variation in disintegration and mucoadhesion
Guggi, D.; Marschütz, M.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 2004
Multifunctional polymeric excipients in non-invasive delivery of hydrophilic macromolecular drugs: the thiomer technology
Kafedjiiski, K.
The Drug Delivery Companies Report, 2004
Thiomers: development and in vitro evaluation of a peroral microparticulate peptide delivery system
Krauland, A.; Bernkop-Schnürch, A.
European Journal of Pharmaceutics and Biopharmaceutics, 2004
Oral insulin delivery: the potential of thiolated chitosan–insulin tablets on non-diabetic rats
Krauland, A.; Guggi, D.; Bernkop-Schnürch, A.
Journal of Controlled Release, 2004
Thiomers in noninvasive polypeptide delivery: in vitro and in vivo characterization of a polycarbophil–cysteine/glutathione gel formulation for human growth hormone
Leitner, V.; Guggi, D.; Bernkop-Schnürch, A.
Journal of Pharmaceutical Sciences, 2004
Polymer–enzyme inhibitor conjugates: influence of the molecular mass on the inhibition of membrane-bound aminopeptidase N activity
Leitner, V.; Bernkop-Schnürch, A.
Journal of Drug Delivery Science and Technology, 2004
Nasal delivery of human growth hormone: in vitro and in vivo evaluation of a thiomer/glutathione microparticulate delivery system
Leitner, V.; Guggi, D.; Krauland, A.; Bernkop-Schnürch, A.
Journal of Controlled Release, 2004
Mucoadhesive thiolated chitosans as platforms for oral controlled drug delivery: synthesis and in vitro evaluation
Roldo, M.; Hornof, M.; Caliceti, P.; Bernkop-Schnürch, A.
European Journal of Pharmaceutics and Biopharmaceutics, 2004
Preparation and in vitro characterization of poly(acrylic acid)–cysteine microparticles
Bernkop-Schnürch, A.; Egger, C.; Elhassan, I. M.; Krauland, A.
Journal of Controlled Release, 2003
Thiolated polymers – thiomers: modification of chitosan with 2-iminothiolane
Bernkop-Schnürch, A.; Hornof, M.; Zoidl, T.
International Journal of Pharmaceutics, 2003
Development and in vitro evaluation of a mucoadhesive oral delivery system for antisense oligonucleotides
Bernkop-Schnürch, A.; Telsnig, J.; Hornof, M.
Scientia Pharmaceutica, 2003
In vitro evaluation of polymeric excipients protecting calcitonin against degradation by intestinal serine proteases
Guggi, D.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 2003
In vivo evaluation of an oral salmon calcitonin-delivery system based on a thiolated chitosan carrier matrix
Guggi, D.; Kast, C. E.; Bernkop-Schnürch, A.
Pharmaceutical Research, 2003
Systemic peptide delivery via the stomach: in vivo evaluation of an oral dosage form for salmon calcitonin
Guggi, D.; Krauland, A. H.; Bernkop-Schnürch, A.
Journal of Controlled Release, 2003
In vitro evaluation of the viscoelastic properties of chitosan–thioglycolic acid conjugates
Hornof, M. D.; Kast, C. E.; Bernkop-Schnürch, A.
European Journal of Pharmaceutics and Biopharmaceutics, 2003
A mucoadhesive ocular insert: development and in vivo evaluation in humans
Hornof, M. D.; Weyenberg, W.; Ludwig, A.; Bernkop-Schnürch, A.
Journal of Controlled Release, 2003
Evidence for the interpenetration of mucoadhesive polymers into the mucus gel layer
Imam, M. E.; Hornof, M.; Valenta, C.; Bernkop-Schnürch, A.
STP Pharma Sciences, 2003
Chitosan–thioglycolic acid conjugate: a new scaffold material for tissue engineering?
Kast, C. E.; Frick, W.; Losert, U.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 2003
Development and in vivo evaluation of an oral delivery system for low molecular weight heparin based on thiolated polycarbophil
Kast, C. E.; Guggi, D.; Langoth, N.; Bernkop-Schnürch, A.
Pharmaceutical Research, 2003
Improvement in the in situ gelling properties of deacetylated gellan gum by the immobilization of thiol groups
Krauland, A. H.; Leitner, V. M.; Bernkop-Schnürch, A.
Journal of Pharmaceutical Sciences, 2003
Development of buccal drug delivery systems based on a thiolated polymer
Langoth, N.; Kalbe, J.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 2003
Mucoadhesive and cohesive properties of poly(acrylic acid)–cysteine conjugates with regard to their molecular mass
Leitner, V. M.; Marschütz, M. K.; Bernkop-Schnürch, A.
European Journal of Pharmaceutical Sciences, 2003
Thiolated polymers: evidence for the formation of disulphide bonds with mucus glycoproteins
Leitner, V. M.; Walker, G. F.; Bernkop-Schnürch, A.
European Journal of Pharmaceutics and Biopharmaceutics, 2003
Thiolated polymers: stability of thiol moieties under different storage conditions
Bernkop-Schnürch, A.; Hornof, M. D.; Kast, C. E.; Langoth, N.
Scientia Pharmaceutica, 2002
The role of glutathione in the permeation enhancing effect of thiolated polymers
Clausen, A. E.; Kast, C. E.; Bernkop-Schnürch, A.
Pharmaceutical Research, 2002
In vitro evaluation of the permeation enhancing effect of polycarbophil–cysteine conjugates on the cornea of rabbits
Hornof, M. D.; Bernkop-Schnürch, A.
Journal of Pharmaceutical Sciences, 2002
Influence of the molecular mass on the permeation enhancing effect of different poly(acrylates)
Kast, C. E.; Bernkop-Schnürch, A.
STP Pharma Sciences, 2002
Polymer–cystamine conjugates: new mucoadhesive excipients for drug delivery?
Kast, C. E.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 2002
Design and in vitro evaluation of a novel bioadhesive vaginal drug delivery system for clotrimazole
Kast, C. E.; Valenta, C.; Leopold, M.; Bernkop-Schnürch, A.
Journal of Controlled Release, 2002
Thiolated polymers: advance in mucoadhesion by use of in-situ crosslinking poly(acrylic acid)–cysteine conjugates
Marschütz, M. K.; Bernkop-Schnürch, A.
European Journal of Pharmaceutical Sciences, 2002
Improvement of the enzymatic stability of a cytotoxic T-lymphocyte epitope model peptide for its oral administration
Marschütz, M. K.; Zauner, W.; Mattner, F.; Otava, A.; Buschle, M.; Bernkop-Schnürch, A.
Peptides, 2002
Evaluation of the inhibitory effect of thiolated poly(acrylates) on vaginal membrane-bound aminopeptidase N
Valenta, C.; Marschütz, M.; Egyed, Ch.; Bernkop-Schnürch, A.
Journal of Pharmacy and Pharmacology, 2002
Peptidase activity on the surface of the porcine buccal mucosa
Walker, G. F.; Langoth, N.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 2002
Mucoadhesive Polymers
Bernkop-Schnürch, A.
Polymeric Biomaterials, Revised and Expanded, 2001
Synthesis and In vitro evaluation of chitosan–thioglycolic acid conjugates
Bernkop-Schnürch, A.; Hopf, T. E.
Scientia Pharmaceutica, 2001
Thiolated polymers: synthesis and in vitro evaluation of polymer–cysteamine conjugates
Bernkop-Schnürch, A.; Clausen, A. E.; Hnatyszyn, M.
International Journal of Pharmaceutics, 2001
Improvement in the mucoadhesive properties of alginate by the covalent attachment of cysteine
Bernkop-Schnürch, A.; Kast, C. E.; Richter, M. F.
Journal of Controlled Release, 2001
Thiolation of polycarbophil enhances its inhibition of soluble and intestinal brush border membrane-bound aminopeptidase N
Bernkop-Schnürch, A.; Zarti, H.; Walker, G. F.
Journal of Pharmaceutical Sciences, 2001
Thiolated carboxymethylcellulose: in vitro evaluation of its permeation enhancing effect on peptide drugs
Clausen, A. E.; Bernkop-Schnürch, A.
European Journal of Pharmaceutics and Biopharmaceutics, 2001
Development and in vitro evaluation of a peptide drug delivery system based on thiolated polycarbophil
Clausen, A. E.; Bernkop-Schnürch, A.
Pharmazeutische Industrie, 2001
Direct compressible polymethacrylic acid–starch compositions for site-specific drug delivery
Clausen, A. E.; Bernkop-Schnürch, A.
Journal of Controlled Release, 2001
Thiolated polymers: development and in vitro evaluation of chitosan–thioglycolic acid conjugates
Kast, C. E.; Bernkop-Schnürch, A.
Biomaterials, 2001
Design and in vitro evaluation of a mucoadhesive oral delivery system for a model (poly)peptide antigen
Marschütz, M. K.; Puttipipatkhachorn, S.; Bernkop-Schnürch, A.
Pharmazie, 2001
Influence of the spacer on the inhibitory effect of different polycarbophil–protease inhibitor conjugates
Marschütz, M. K.; Veronese, F. M.; Bernkop-Schnürch, A.
European Journal of Pharmaceutics and Biopharmaceutics, 2001
Development and in vitro evaluation of a mucoadhesive vaginal delivery system for progesterone
Valenta, C.; Kast, E. C.; Harich, I.; Bernkop-Schnürch, A.
Journal of Controlled Release, 2001
Thiolated polymers: development and evaluation of transdermal delivery systems for progesterone
Valenta, C.; Walzer, A.; Clausen, A. E.; Bernkop-Schnürch, A.
Pharmaceutical Research, 2001
Design and in vivo evaluation of an oral delivery system for insulin
Marschütz, M. K.; Caliceti, P.; Bernkop-Schnürch, A.
Pharmaceutical Research, 2000
In vitro evaluation of the permeation-enhancing effect of thiolated polycarbophil
Clausen, A. E.; Bernkop-Schnürch, A.
Journal of Pharmaceutical Sciences, 2000
The use of multifunctional polymers for non-invasive peptide and protein application
Bernkop-Schnürch, A.
Expert Opinion on Therapeutic Patents, 2000
Polycarbophil–cysteine conjugates as platforms for oral polypeptide delivery systems
Bernkop-Schnürch, A.; Thaler, S. C.
Journal of Pharmaceutical Sciences, 2000
Oral peptide drug delivery: polymer–inhibitor conjugates protecting insulin from enzymatic degradation in vitro
Marschütz, M. K.; Bernkop-Schnürch, A.
Biomaterials, 2000
Development of controlled drug release systems based on thiolated polymers
Bernkop-Schnürch, A.; Scholler, S.; Biebel, R. G.
Journal of Controlled Release, 2000
Valaminols, probably the most simplified peptide-analogs acting as pepsin inhibitors
Kratzel, M.; Bernkop-Schnürch, A.
Peptides, 2000
Synthesis and characterisation of mucoadhesive thiolated polymers
Bernkop-Schnürch, A.; Steininger, S.
International Journal of Pharmaceutics, 2000
Chitosan and its derivatives: potential excipients for peroral peptide delivery systems
Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 2000
Peroral administration of enzymes: strategies to improve the galenic of dosage forms for trypsin and bromelain
Bernkop-Schnürch, A.; Giovanelli, R.; Valenta, C.
Drug Development and Industrial Pharmacy, 2000
Anionic mucoadhesive polymers as auxiliary agents for the peroral administration of (poly)peptide drugs: influence of the gastric juice
Bernkop-Schnürch, A.; Gilge, B.
Drug Development and Industrial Pharmacy, 2000
α-Liponsäure (-Derivate) enthaltende Retardform
Bernkop-Schnürch, A.; Schuhbauer, H.; Pischel, I.
Deutsche Patentschrift, 1999
Peroral polypeptide delivery
Bernkop-Schnürch, A.; Valenta, C.; Daee, S. M.
Arzneimittelforschung, 1999
Deoxycholate-hydrogels: novel drug carrier systems for topical use
Valenta, C.; Nowack, E.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 1999
Simplified pepstatins: Synthesis and evaluation of N-terminally modified analogues
Kratzel, M.; Schlichtner, B.; Kirchmayer, R.; Bernkop-Schnürch, A.
Journal of Medicinal Chemistry, 1999
Polymers with thiol groups: a new generation of mucoadhesive polymers?
Bernkop-Schnürch, A.; Schwarz, V.; Steininger, S.
Pharmaceutical Research, 1999
Comparative in vitro study of different chitosan-complexing agent conjugates
Bernkop-Schnürch, A.; Freudl, J.
Die Pharmazie, 1999
Muco-adhesive polymers, use thereof and method for producing the same
Bernkop-Schnürch, A.
US Patent US 7,354,600 B1; EP Patent EP 1126881 B1; WO Patent WO 00/25823, 1999
Synthesis, development and in vitro evaluation of drug delivery systems with protective effect against degradation by pepsin
Bernkop-Schnürch, A.; Kirchmayer, R.; Kratzel, M.
Journal of Drug Targeting, 1999
Polymer/inhibitor conjugates — a promising strategy to overcome the enzymatic barrier to perorally administered (poly)peptide drugs?
Bernkop-Schnürch, A.
STP Pharma Sciences, 1999
Synthesis and in vitro evaluation of chitosan-cysteine conjugates
Bernkop-Schnürch, A.; Brandt, U.-M.; Clausen, A. E.
Scientia Pharmaceutica, 1999
Lysozyme–caffeic acid conjugates: possible novel preservatives for dermal formulations
Valenta, C.; Schwarz, E.; Bernkop-Schnürch, A.
International Journal of Pharmaceutics, 1998
Synthesis and evaluation of lysozyme derivatives exhibiting an enhanced antimicrobial action
Bernkop-Schnürch, A.; Krist, S.; Vehabovic, M.; Valenta, C.
European Journal of Pharmaceutical Sciences, 1998
Auxiliary agents for the peroral administration of peptide and protein drugs: Synthesis and evaluation of novel pepstatin analogues
Kratzel, M.; Hiessböck, R.; Bernkop-Schnürch, A.
Journal of Medicinal Chemistry, 1998
Basic studies on bioadhesive delivery systems for peptide and protein drugs
Bernkop-Schnürch, A.; Humenberger, C.; Valenta, C.
International Journal of Pharmaceutics, 1998
Chitosan–EDTA conjugate: a novel polymer for topical gels
Valenta, C.; Christen, B.; Bernkop-Schnürch, A.
Journal of Pharmacy and Pharmacology, 1998
Intestinal peptide and protein delivery: Novel bioadhesive drug-carrier matrix shielding from enzymatic attack
Bernkop-Schnürch, A.; Pasta, M.
Journal of Pharmaceutical Sciences, 1998
The use of inhibitory agents to overcome the enzymatic barrier to perorally administered therapeutic peptides and proteins
Bernkop-Schnürch, A.
Journal of Controlled Release, 1998
Synthesis and in vitro evaluation of chitosan-EDTA-protease-inhibitor conjugates which might be useful in oral delivery of peptides and proteins
Bernkop-Schnürch, A.; Scerbe-Saiko, A.
Pharmaceutical Research, 1998
Mucoadhesive polymers as platforms for peroral peptide delivery and absorption: synthesis and evaluation of different chitosan–EDTA conjugates
Bernkop-Schnürch, A.; Krajicek, M. E.
Journal of Controlled Release, 1998
INTESTINAL PEPTIDE AND PROTEIN DELIVERY: SYNTHESIS AND EVALUATION OF CHITOSAN-EDTA-BOWMAN-BIRK INHIBITOR CONJUGATES
Bernkop-Schnürch, A.; Pasta, M.
Pharmaceutical Technology Conference, 1998
INFLUENCE OF IONIC CROSSLINKERS ON COHESIVENESS OF BIOADHESIVE POLYMERS USED AS (POLY)PEPTIDE DRUG CARRIER MATRICES
Bernkop-Schnürch, A.; Humenberger, C.; Valenta, C.
Pharmaceutical Technology Conference, 1998
Development and in vitro evaluation of a drug delivery system based on chitosan-EDTA BBI conjugate
Bernkop-Schnürch, A.; Krauland, A.; Valenta, C.
Journal of Drug Targeting, 1998
Development and in vitro evaluation of a drug delivery system protecting from trypsinic degradation
Bernkop-Schnürch, A.; Bratengeyer, I.; Valenta, C.
International Journal of Pharmaceutics, 1997
Modified mucoadhesive polymers for the peroral administration of mainly elastase degradable therapeutic (poly)peptides
Bernkop-Schnürch, A.; Schwarz, G. H.; Kratzel, M.
Journal of Controlled Release, 1997
Bioadhesion to the intestine by means of E. coli K99-fimbriae: Gastrointestinal stability and specificity of adherence
Gabor, F.; Bernkop-Schnürch, A.; Hamilton, G.
European Journal of Pharmaceutical Sciences, 1997
Novel bioadhesive chitosan-EDTA conjugate protects leucine enkephalin from degradation by aminopeptidase N
Bernkop-Schnürch, A.; Paikl, C.; Valenta, C.
Pharmaceutical Research, 1997
Modification of lysozyme with cinnamaldehyde: a strategy for constructing novel preservatives for dermatics
Valenta, C.; Bernkop-Schnürch, A.; Schwartz, M.
International Journal of Pharmaceutics, 1997
Development and in vitro evaluation of systems to protect peptide drugs from aminopeptidase N
Bernkop-Schnürch, A.; Marschütz, M. K.
Pharmaceutical Research, 1997
Synthesis and evaluation of a modified mucoadhesive polymer protecting from α-chymotrypsinic degradation
Bernkop-Schnürch, A.; Apprich, I.
International Journal of Pharmaceutics, 1997
Strategien zur peroralen Applikation von Peptid- und Proteinwirkstoffen
Bernkop-Schnürch, A.
Scientia Pharmaceutica, 1997
Bacterial adhesins as a drug carrier: covalent attachment of K99 fimbriae to 6-methylprednisolone
Bernkop-Schnürch, A.; Gabor, F.; Spiegl, P.
Die Pharmazie, 1997
Development and analysis of a polymer protecting from luminal enzymatic degradation caused by α-chymotrypsin
Bernkop-Schnürch, A.; Gockel, N. C.
Drug Development and Industrial Pharmacy, 1997
The antistaphylococcal effect of nisin in a suitable vehicle: a potential therapy for atopic dermatitis in man
Valenta, C.; Bernkop-Schnürch, A.; Rigler, H. P.
Journal of Pharmacy and Pharmacology, 1996
Investigations into the diffusion behaviour of polypeptides in native intestinal mucus with regard to their peroral administration
Bernkop-Schnürch, A.; Fragner, R.
Pharmacy and Pharmacology Communications, 1996
Novel bioadhesive drug delivery system protecting (poly)peptides from gastric enzymatic degradation
Bernkop-Schnürch, A.; Dundalek, K.
International Journal of Pharmaceutics, 1996
Nisin, a potential preservative for topical preparations
Valenta, C.; Bernkop-Schnürch, A.; Teltscher, C.
Die Pharmazie, 1996
In vitro skin permeation studies of the lantibiotic nisin
Bernkop-Schnürch, A.; Valenta, C.; Gatterwe, V.
European Journal of Pharmaceutics and Biopharmaceutics, 1996
An adhesive drug delivery system based on K99-fimbriae
Bernkop-Schnürch, A.; Gabor, F.; Szostak, M. P.; Lubitz, W.
European Journal of Pharmaceutical Sciences, 1995
Mikrobielle Stabilität von magistral hergestellten Dermatika
Bernkop-Schnürch, A.; Valenta, C.; Urban, U.
Scientia Pharmaceutica, 1995
Gentechnologische Herstellung bioadhäsiver Arzneistoffträger
Bernkop-Schnürch, A.
1994
Mucoadhesive Polymers
Bernkop-Schnürch, A.
Polymeric Biomaterials, 147–166, 1994