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Khush Bakhat Afzal

Khush Bakhat Afzal

PhD Candidate

Department of Pharmaceutical Technology

Institute of Pharmacy

University of Innsbruck

About

Current research interests are related to targeting the oncogenes to study their mechanism and analysis of oncoprotein targeting strategies. Research interests include the design and evaluation of cationic auxiliary agents for nucleic acids and proteins (monobodies) delivery.

Her projects include developing and evaluating various delivery systems like nanoparticles, self-emulsifying drug delivery systems, as well as zwitterionic delivery systems facilitating the drugs, nucleic acids, and peptide delivery to the targeted sites.

Publications

  • Quaternary ammonium-modified dextran: a unique biodegradable mucoadhesive polymer Afzal, Khush Bakhat, et al. “Quaternary ammonium-modified dextran: a unique biodegradable mucoadhesive polymer.” European Journal of Pharmaceutics and Biopharmaceutics (2025): 114788. https://doi.org/10.1016/j.ejpb.2025.114788

  • Assessing the Potential of Chlorido[N,N’-bis(salicylidene)-1,2-phenylenediamine]iron(III): Exploring Delivery Through Lipid-Based Nanocarriers Schmidt, Marlene Ramona, et al. “Assessing the Potential of Chlorido [N, N’-bis (salicylidene)-1, 2-phenylenediamine] iron (III): Exploring Delivery Through Lipid-Based Nanocarriers.” European Journal of Pharmaceutical Sciences (2025): 107206. https://doi.org/10.1016/j.ejps.2025.107206

  • Cyclodextrin-based polyrotaxanes: Cellular uptake enhancement effect of different functionality types Gintsburg, David, et al. “Cyclodextrin-based polyrotaxanes: cellular uptake enhancement effect of different functionality types.” Carbohydrate Polymer Technologies and Applications (2025): 100981.https://doi.org/10.1016/j.carpta.2025.100981

  • Peptide Drug Delivery: Permeation Behaviour and Intracellular Fate of Hydrophobic Ion Pairs in Self-Emulsifying Drug Delivery Systems Truszkowska, Martyna, et al. “Peptide Drug Delivery: Permeation Behaviour and Intracellular Fate of Hydrophobic Ion Pairs in Self-Emulsifying Drug Delivery Systems.” European Journal of Pharmaceutical Sciences (2025): 107207. https://doi.org/10.1016/j.ejps.2025.107207

  • About the Impact of Hydrophilic Organic Solvents on the Emulsifying Properties of Self-Emulsifying Drug Delivery Systems (Sedds) Saleh, Ahmad, et al. “About the Impact of Hydrophilic Organic Solvents on the Emulsifying Properties of Self-Emulsifying Drug Delivery Systems (Sedds).” Available at SSRN 5202128.https://dx.doi.org/10.2139/ssrn.5202128