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Ilaria Polidori

Ilaria Polidori

PhD Candidate

Department of Pharmaceutical Technology

Institute of Pharmacy

University of Innsbruck

About

Focusing on the development of innovative formulation strategies for biologics and nucleic acids

Research focus on the optimization of lipid-based nanocarriers for oral and parenteral use to achieve efficient intracellular drug delivery

Publications

  • Polidori I, To D, Kali G, Bernkop-Schnürch A. Histidine-based ionizable cationic surfactants: novel biodegradable agents for hydrophilic macromolecular drug delivery. Drug Deliv Transl Res. 2024 Sep;14(9):2370-2385. doi: 10.1007/s13346-023-01511-8.

  • Stengel D, Jörgensen AM, Polidori I, Kapitza P, Ricci F, Bernkop-Schnürch A. The power of sulfhydryl groups: Thiolated lipid-based nanoparticles enhance cellular uptake of nucleic acids. J Colloid Interface Sci. 2023 Oct 18;654(Pt B):1136-1145. doi: 10.1016/j.jcis.2023.10.039.

  • To D, Steinbring C, Weber LI, Ricci F, Polidori I, Postina A, Hartl M, Bernkop-Schnürch A. Design of lipid-based formulations for oral delivery of a BASP1 peptide targeting MYC-dependent gastrointestinal cancer cells. J Control Release. 2025 Jun 10;382:113677. doi: 10.1016/j.jconrel.2025.113677.

  • Gintsburg D, Kreuzer P, Bakhat Afzal K, Polidori I, Truszkowska M, Seybold A, Bernkop-Schnürch A, Kali G. Cyclodextrin-based polyrotaxanes: cellular uptake enhancement effect of different functionality types. Carbohydr Polym Technology and Applications. 2025 Sep; doi: 10.1016/j.carpta.2025.100981